Results 111 to 120 of about 1,221,070 (279)

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology

Annals of Neurology, EarlyView.
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby, Xiaojie Liu, Melinda Wojtkiewicz, Linda Berg Luecke, Rebekah L. Gundry, Qing‐Song Liu, Allison D. Ebert   +6 more
wiley   +1 more source

Optimizing Strategies for Non‐Invasive Prospection of Settlements in the Intertidal Zone: A Case Study From the Centre of the Drowned Medieval Village of Tolsende (Scheldt Estuary, the Netherlands)

Archaeological Prospection, EarlyView.
ABSTRACT Medieval and early modern drowned villages in the intertidal zone of the Scheldt estuary (the Netherlands) constitute intriguing yet largely understudied components of north‐western Europe's underwater cultural heritage. Despite their high archaeological potential as time capsules of past settlement landscapes, research has remained limited ...
Jan Trachet, Sarah Bäumler, Stefan Krojer, Jeroen Verhegge, Wim De Clercq, Philippe De Smedt, Wouter H. Maes, Bente S. Majchczack, Immo Trinks, Dennis Wilken   +9 more
wiley   +1 more source

Scanning Parametric Sediment Echosounder as Tool for Underwater Archaeological Prospection

Archaeological Prospection, EarlyView.
ABSTRACT Underwater cultural heritage 3D prospection techniques, especially for remains that are partly buried in the ground, are only very rarely available and often can only be applied with considerable technical effort. To overcome this limitation, we evaluate a methodological adaption of widely used and available single channel parametric sediment ...
Dennis Wilken, Philipp Held, Jacob Geersen, Marcel Bradtmöller, Peter Feldens, Jens Schneider v. Deimling   +5 more
wiley   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Statistically robust design for the all-electric ship from a network theoretic perspective

, 2009
Recent progress in understanding the robustness properties of large-scale networks leads one to consider how such results can inform design of the all-electric ship. Network robustness seems to be correlated with certain statistical properties, which may
Franz S. Hover, Josh A. Taylor, Taylor, Joshua Adam, Hover, Franz S.   +3 more
core   +1 more source

Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women

British Journal of Clinical Pharmacology, EarlyView.
Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea, Andrew Litovsky, Prachi Wickremasingha, Nairita Ghosal, Brad Roadcap, Robert Valesky, Robin Lee, Leea D. Reed, Ming Wang, Wei Fang, Rebecca Wrishko   +10 more
wiley   +1 more source

Corporate Decarbonization via Technology and Management

Business Strategy and the Environment, EarlyView.
ABSTRACT This study provides a comprehensive overview of key findings on decarbonization, advanced technologies, and management strategies, highlighting emerging themes shaping the field. Advanced technologies enhance carbon reduction through efficiency, real‐time monitoring, and optimizing resource optimization.
Heidy Montero‐Teran, Rudolf R. Sinkovics, Olli Kuivalainen   +2 more
wiley   +1 more source

SABR: Ship Anti Ballistic Response

, 2006
Web page capture of TSSE Team 2006 - SABR: Ship Anti Ballistic Response project page, as it appeared July 2, 2025.Based on public law and Presidential mandate, ballistic missile defense development is a front-burner issue for homeland defense and the ...

core  

An Analysis of Transient Overvoltages during the Energization of Electric Ship Propulsion Systems. [PDF]

ScientificWorldJournal, 2015
Brenna M, Foiadelli F, Zaninelli D.
europepmc   +1 more source

Digital Technologies for Transparent and Sustainable Supply Chain Management: A Resource Orchestration‐Based View in the Textile Industry

Business Strategy and the Environment, EarlyView.
ABSTRACT Implementing digital technologies is touted as the next big step for the firms aiming to improve sustainability in their supply chains. These technologies are often credited with the potential to improve transparency and achieve sustainability.
Amna Farrukh, Aqeel Ahmed, Sadaat Yawar
wiley   +1 more source