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FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu+5 more
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Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang+16 more
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Functional electrical stimulation [PDF]
In the health-care professions, electrical stimulation is used for three purposes: to aid diagnosis; as a therapeutic tool; and to restore lost or damaged functions. Functional electrical stimulation (FES) and functional neurostimulation (FNS) are terms which are more or less interchangeable, and which encompass the third of these purposes.
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Electrical stimulation of teeth
Pain, 1976The technical problems of stimulating intact teeth in clinical diagnosis and in pain research are discussed. Bipolar stimulation has no advantage over monopolar stimulation for most applications. A 100 V constant current stimulator is suitable for monopolar stimulation of healthy teeth with a large electrode at about threshold intensity, but, for ...
B Matthews, B N Searle
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Extracochlear Electrical Stimulation
Scandinavian Audiology, 1984Extracochlear electrical stimulation was carried out in 7 patients. We used square-wave signals. Electrode positions at the oval and round window showed the lowest current thresholds. The threshold of sound sensations elicited by electrical stimulation was higher in the high frequency than in the low frequency range.
J. Randa+2 more
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Electrical Stimulation and Magnetic Stimulation*
2023With respect to lower urinary tract dysfunctions, electrical stimulation (ES) is applied, particularly to the pelvic floor muscles, bladder, and sacral nerve roots. The ES of the pelvic floor aims at stimulating motor fibres of the pudendal nerve, which may elicit a direct contraction of the pelvic floor muscles or the striated peri-urethral ...
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Extracochlear Electrical Stimulation
Artificial Organs, 1989Abstract: Twelve patients with sensorineural hearing loss were stimulated by a transtympanic electrode contacting the cochlear promontory. Nine of them were tested to study hearing perception associated with various features of electrical signals, using an auditory electrical stimulator. Biphasic pulse bursts and sine‐wave bursts were used as stimuli.
Silvano Zanutto+5 more
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Electrical stimulation of breathing
Human Physiology, 2010We have generalized data on different breathing electrostimulation methods and have shown their merits and demerits. We have presented electrostimulation methods, the electrostimulators description, different variants of electrodes site, parameters influence. It has shown advantages breathing electrostimulation application in a medical practice.
V. A. Safonov, N. N. Tarasova
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