Results 41 to 50 of about 248,512 (330)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Delay-Dependent Response in Weakly Electric Fish under Closed-Loop Pulse Stimulation. [PDF]

PLoS ONE, 2015
In this paper, we apply a real time activity-dependent protocol to study how freely swimming weakly electric fish produce and process the timing of their own electric signals. Specifically, we address this study in the elephant fish, Gnathonemus petersii,
Caroline Garcia Forlim, Reynaldo Daniel Pinto, Pablo Varona, Francisco B Rodríguez   +3 more
doaj   +1 more source

Intestinal Electric Stimulation Accelerates Whole Gut Transit and Promotes Fat Excrement in Conscious Rats [PDF]

, 2009
*_Introduction:_* Intestinal electric stimulation (IES) is proposed as a potential tool for the treatment of morbid obesity. Our previous study showed that IES with one pair of electrodes accelerated intestinal transit and decreased fat absorption in a ...
Jiande Chen, Ying Sun
core   +2 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

The Spatial Structure of Stimuli Shapes the Timescale of Correlations in Population Spiking Activity [PDF]

, 2012
Throughout the central nervous system, the timescale over which pairs of neural spike trains are correlated is shaped by stimulus structure and behavioral context.
Abigail Morrison, Ashok Litwin-Kumar, Brent Doiron, Maurice J. Chacron   +3 more
core   +4 more sources

Biomedical applications of electrical stimulation [PDF]

Cellular and Molecular Life Sciences, 2020
This review provides a comprehensive overview on the biomedical applications of electrical stimulation (EStim). EStim has a wide range of direct effects on both biomolecules and cells. These effects have been exploited to facilitate proliferation and functional development of engineered tissue constructs for regenerative medicine applications.
Siwei Zhao, Abijeet Singh Mehta, Min Zhao   +2 more
openaire   +5 more sources

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Acupuncture and percutaneous electric nerve stimulation to control chronic masticatory myalgia: preliminary study

Revista Dor
BACKGROUND AND OBJECTIVES:This was a randomized clinical trial to compare the analgesic effect of acupuncture and percutaneous electric nerve stimulation for chronic masseter muscle masticatory myalgia.METHODS:Participated in the study 23 patients with ...
Cyntia de Medeiros Nogueira, Michele Gomes do Nascimento, Andreana Braga de Morais Malouf, Maria do Socorro Catanho Pereira de Lyra Didier, Arnaldo de França Caldas Júnior, Mauricio Kosminsky   +5 more
doaj   +1 more source

Transcranial Direct Current Stimulation Optimization – From Physics-Based Computer Simulations to High-Fidelity Head Phantom Fabrication and Measurements

Frontiers in Human Neuroscience, 2019
BackgroundTranscranial direct current stimulation (tDCS) modulates neural networks. Computer simulations, while used to identify how currents behave within tissues of different conductivity properties, still need to be complemented by physical models ...
Leon Morales-Quezada, Mirret M. El-Hagrassy, Beatriz Costa, R. Andy McKinley, Pengcheng Lv, Felipe Fregni   +5 more
doaj   +1 more source