Results 61 to 70 of about 3,838,008 (411)

Delay-Dependent Response in Weakly Electric Fish under Closed-Loop Pulse Stimulation. [PDF]

open access: yesPLoS ONE, 2015
In this paper, we apply a real time activity-dependent protocol to study how freely swimming weakly electric fish produce and process the timing of their own electric signals. Specifically, we address this study in the elephant fish, Gnathonemus petersii,
Caroline Garcia Forlim   +3 more
doaj   +1 more source

Modeling transcranial magnetic stimulation from the induced electric fields to the membrane potentials along tractography-based white matter fiber tracts [PDF]

open access: yes, 2016
Objective. Transcranial magnetic stimulation (TMS) is a promising non-invasive tool for modulating the brain activity. Despite the widespread therapeutic and diagnostic use of TMS in neurology and psychiatry, its observed response remains hard to predict,
Crevecoeur, Guillaume   +2 more
core   +2 more sources

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

Establishment of a Numerical Model to Design an Electro-Stimulating System for a Porcine Mandibular Critical Size Defect

open access: yesApplied Sciences, 2019
Electrical stimulation is a promising therapeutic approach for the regeneration of large bone defects. Innovative electrically stimulating implants for critical size defects in the lower jaw are under development and need to be optimized in silico and ...
Hendrikje Raben   +3 more
doaj   +1 more source

Design and Fabrication of Novel Digital Transcranial Electrical Stimulator for Medical and Psychiatry Applications [PDF]

open access: yesarXiv, 2020
In this article, we design a novel Transcranial Electrical Stimulator for medical applications, which is very cheap and can produce the desired signals very accurately. Our fabricated stimulator generates all current signals related to Transcranial Electrical Stimulation (TES) methods, i.e.
arxiv  

Long-term changes in functional connectivity predict responses to intracranial stimulation of the human brain [PDF]

open access: yesarXiv, 2021
Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is crucial for any therapeutic use of brain stimulation.
arxiv  

Biomedical applications of electrical stimulation [PDF]

open access: yesCellular and Molecular Life Sciences, 2020
This review provides a comprehensive overview on the biomedical applications of electrical stimulation (EStim). EStim has a wide range of direct effects on both biomolecules and cells. These effects have been exploited to facilitate proliferation and functional development of engineered tissue constructs for regenerative medicine applications.
Siwei Zhao   +2 more
openaire   +5 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Transcranial stimulability of phosphenes by long lightning electromagnetic pulses [PDF]

open access: yesPhysics Letters A, Volume 347, Issue 29, pp. 2932-2935 (2010). Erratum and addendum: Physics Letters A, Volume 347, Issue 47, pp. 4797-4799 (2010), 2010
The electromagnetic pulses of rare long (order of seconds) repetitive lightning discharges near strike point (order of 100m) are analyzed and compared to magnetic fields applied in standard clinical transcranial magnetic stimulation (TMS) practice. It is shown that the time-varying lightning magnetic fields and locally induced potentials are in the ...
arxiv   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

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