Results 71 to 80 of about 99,375 (350)

Focused and Deep Brain Magnetic Stimulation Using New Coil Design in Mice [PDF]

, 2013
Deep brain transcranial magnetic stimulation (TMS) offers promising treatment for neurological disorders that originate from deeper regions of the brain, such as Parkinson\u27s disease.
Crowther, Lawrence, Hadimani, Ravi, Hadimani, Ravi, Jiles, David, Jiles, David, March, S., McAtee, S., Senter, M., Spoth, K., Stiner, Daniel   +9 more
core   +3 more sources

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Advances in neuromodulation for treatment of prolonged disorders of consciousness

Chinese Journal of Contemporary Neurology and Neurosurgery
Neuromodulation has emerged as a significant clinical treatment modality for patients with prolonged disorders of consciousness (pDOC), encompassing both non⁃invasive and invasive neuromodulation techniques.
HE Chen, SONG Ming, XU Long
doaj   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Recent Trends in Electrical Stimulation Therapy.

Journal of exercise physiology, 1994
1991年から1993年までの3年間における国内の理学療法士の論文，学会発表と，同時期のPhysical Therapy誌における論文の比較から，電気刺激療法に関する最近の傾向と問題点を探った。国内の学会では，筋力増強のための電気刺激療法，Physical Therapy誌では，創傷・潰瘍治癒，浮腫抑制のための電気刺激療法に関するものが多くみられた。また，Physlcal Therapy誌では動物を対象とした基礎的研究に関する論文がみられるのも特徴的であった。これらのことから，従来より指摘されている，より基礎的な研究による作用メカニズムの解明が必要なことが改めて示唆された。
openaire   +2 more sources

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Maintenance deep transcranial magnetic stimulation sessions are associated with reduced depressive relapses in patients with unipolar or bipolar depression [PDF]

, 2015
Introduction: Deep transcranial magnetic stimulation (dTMS) is a new form of TMS allowing safe stimulation of deep brain regions. The objective of this preliminary study was to assess the role of dTMS maintenance sessions in protecting patients with ...
ANGELETTI, Gloria, BERSANI, FRANCESCO SAVERIO, DEL CASALE, ANTONIO, DI PIETRO, SIMONE, Ferri, Vittoria R., GIRARDI, Paolo, Imperatori, Claudio, KOTZALIDIS, GEORGIOS, Raccah, Ruggero N., RAPINESI, CHIARA, SERATA, DANIELE, Zangen, Abraham   +11 more
core   +2 more sources

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

Advanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim, Dai‐Hwan Kim, Priyannth R. Sundharbaabu, Chae Yeon Lee, Jina Bae, Jiyu Hyun, Young‐Ju Jang, Haeni Kim, Min‐Ho Hong, Juewen Liu, Tobias Fey, Suk Ho Bhang, Jun Hyuk Heo, Jung Heon Lee   +13 more
wiley   +1 more source

Electrical Stimulation Technologies for Wound Healing [PDF]

, 2014
Objective: To discuss the physiological bases for using exogenously applied electric field (EF) energy to enhance wound healing with conductive electrical stimulation (ES) devices.
Kloth, Luther C.
core   +2 more sources