Results 121 to 130 of about 553 (263)

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Symmetrical pH Electrochemical Cell Coupled to Constant Potential Coulometry for Improved Sensitivity and Precision: Part 2. Submersible Probe for In Situ Measurements. [PDF]

ACS Meas Sci Au
Nussbaum R, Jeanneret S, Cherubini T, Tercier-Waeber ML, Omanović D, Bakker E.   +5 more
europepmc   +1 more source

Energy conservation prospects in water intensive Paddy-Wheat cropping system for groundwater pumping in the semi-arid region of Haryana. [PDF]

PeerJ, 2023
Singh K, Jhorar RK, Sidhpuria MS, Kumar M, Mehla MK.   +4 more
europepmc   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

JACUZI-SD: An automated, high-throughput, minimally stressful approach to sleep depriving larval zebrafish. [PDF]

iScience
Elias LJ, Khoo H, Kroll F, Zhang C, Hur SC, Rihel J, Blackshaw S.   +6 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Comprehensive energy audit and conservation strategy for public buildings: enhancing energy efficiency and grid sustainability. [PDF]

Sci Rep
Habib S, Tamoor M, Gulzar MM, Murtaza AF, Shafiullah M, Alsafrani A.   +5 more
europepmc   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Optimized design of SynRM drive systems for high-efficiency solar water pumps. [PDF]

Heliyon
Boztas G, Aydogmus O, Yilmaz M.
europepmc   +1 more source

Machine Learning Approach for Predictive Maintenance of the Electrical Submersible Pumps (ESPs). [PDF]

ACS Omega, 2022
Abdalla R, Samara H, Perozo N, Carvajal CP, Jaeger P.   +4 more
europepmc   +1 more source