Results 161 to 170 of about 120,375 (305)

The effect of Transmission Design on Electric Vehicle (EV) Performance [PDF]

open access: yes, 2010
Crolla, Dave   +2 more
core  

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

open access: yesAdvanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu   +10 more
wiley   +1 more source

2019 Electric Vehicles International Conference (EV) [PDF]

open access: yes2019 Electric Vehicles International Conference (EV), 2019
openaire   +2 more sources

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang   +12 more
wiley   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang   +7 more
wiley   +1 more source

Light‐Promoted Hydrazine Dehydrogenation over Ni/NH2‐MIL‐125: Unraveling Mechanisms for Efficient Hydrogen Production

open access: yesAdvanced Science, EarlyView.
Highly dispersed and electron‐rich Ni nanoparticles (≈2.7 nm) supported on NH2‐MIL‐125 significantly promote the dehydrogenation of hydrous hydrazine under visible‐light irradiation, achieving a turnover frequency of 220.2 h−1 at 323 K, which is more than twice that in the dark (108.1 h−1) and outperforms most reported non‐precious metal catalysts ...
Jianjun Long   +6 more
wiley   +1 more source

Reaction Mechanism, Challenges, and Strategies of High‐Energy‐Density Sodium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
Focusing on high‐energy‐density sodium‐ion batteries, this review highlights the advantages offered by conversion‐type cathode materials. The currently studied cathode materials are systematically introduced. By analyzing sulfur, oxygen, and transition metal halides and other conversion‐type cathodes, the key challenges associated with these cathodes ...
Dan Yu   +8 more
wiley   +1 more source

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