Results 41 to 50 of about 5,529,234 (318)
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Hardware Certification for Real-time Safety-critical Systems: State of the Art [PDF]
, 2010 This paper discusses issues related to the RTCA document DO-254 Design Assurance Guidance for Airborne Electronic Hardware and its consequences for hardware certification.
Kornecki, Andrew J., Zalewski, Janusz
core +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source
Electrical stimulation in bone tissue engineering treatments
European Journal of Trauma and Emergency Surgery, 2020 Electrical stimulation (EStim) has been shown to promote bone healing and regeneration both in animal experiments and clinical treatments. Therefore, incorporating EStim into promising new bone tissue engineering (BTE) therapies is a logical next step ...
L. Leppik +3 more
semanticscholar +1 more source
Are Wireless Sensors Feasible for Aircraft? [PDF]
, 2009 Wireless communications is a preferred way of data transmission in many aerospace applications. Replacing some aircraft sensor wiring with wireless communications is a highly desirable but challenging transformation.
Demirkiran, Ilteris +2 more
core +1 more source
Graduate Curricula in Software Engineering and Software Assurance: Need and Recommendations [PDF]
, 2010 In discussions about the development and use of computer systems and software products, the term “professional software engineer” is used repeatedly. In the last two decades there has been significant effort devoted to enhancing and advancing the state ...
Hilburn, T. B., Kornecki, Andrew J.
core +1 more source
EEG Response to Sedation Interruption Complements Behavioral Assessment After Severe Brain Injury
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Accurate assessment of the level of consciousness and potential to recover in patients with severe brain injury underpins crucial decisions in the intensive care unit but remains a major challenge for the clinical team. The neurological wake‐up test is a widely used assessment tool. However, many patients' behavioral responses during
Charlotte Maschke +12 more
wiley +1 more source