Results 151 to 160 of about 203,582 (316)

Prognostic value of global longitudinal strain in hypertrophic cardiomyopathy: A systematic review and meta‐analysis

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1184-1191, December 2022., 2022
Abstract Background As previously reported, impairment of left ventricular global longitudinal strain (LVGLS) is associated with myocardial fibrosis, arrhythmias, and heart failure in hypertrophic cardiomyopathy (HCM) patients. Hypothesis This study aimed to estimate the association between LVGLS measured by echocardiography and major adverse ...
Ying Yang   +3 more
wiley   +1 more source

RESPOSTAS ELETROCARDIOGRÁFICAS DE EQUINOS AO TREINAMENTO COM BASE NA CURVA VELOCIDADE-LACTATO DETERMINADA EM ESTEIRA ROLANTE

open access: yesCiência Animal Brasileira, 2011
The aim of this study was to evaluate, by electrocardiographic analysis, equine cardiovascular adaptations to training based on speed-lactate curve. For this evaluation, eight Arabian horses previously submitted to four months of rest were used.
Raquel Mincarelli Albernaz   +5 more
doaj  

Cyclic Alternating Pattern Dynamics in Individuals at Risk for Developing Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to investigate the differences in cyclic alternating patterns (CAP) metrics, a non‐rapid eye movement (NREM) sleep physiological rhythm, among recently diagnosed patients with Parkinson's disease (PD), and individuals at high and low risk for developing PD based on genetic and prodromal risk.
Andrew Dagay   +5 more
wiley   +1 more source

Pharmacokinetics and Bioequivalence of Fudosteine in Healthy Chinese Volunteers Under Fasting and Fed Conditions: A 4‐Way Replicate Crossover Study

open access: yesClinical Pharmacology in Drug Development, Volume 12, Issue 1, Page 30-37, January 2023., 2023
Abstract The bioequivalence of a generic fudosteine tablet vs a brand‐named fudosteine tablet under fasting and fed conditions was evaluated in this study. This randomized, open‐label, single‐dose, 4‐way replicate, crossover, bioequivalence study included 64 healthy Chinese subjects (fasting cohort, n = 32; fed cohort, n = 32) who were assigned to ...
Mingxue Zhu   +6 more
wiley   +1 more source

Towards Polymer Composite‐Based Transient Electronic Systems

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko   +5 more
wiley   +1 more source

Evaluation of Deutetrabenazine's Potential to Delay Cardiac Repolarization Using Concentration‐QTc Analysis

open access: yesClinical Pharmacology in Drug Development, Volume 12, Issue 1, Page 94-106, January 2023., 2023
Abstract Deutetrabenazine (Austedo) is indicated in adults for chorea associated with Huntington disease and tardive dyskinesia. Escalating deutetrabenazine doses were administered to healthy volunteers who were cytochrome P450 2D6 extensive/intermediate metabolizers (EMs) or poor metabolizers (PMs) to determine pharmacokinetic exposure of parent drug ...
Frank Schneider   +7 more
wiley   +1 more source

Wearable Biomonitoring with 2D Carbon‐Based Nanocomposite Hydrogels

open access: yesAdvanced Physics Research, EarlyView.
This review critically examines recent advancements in nanocomposite hydrogels, emphasizing the reinforcement mechanisms offered by 2D carbon‐based nanomaterials and exploring the various applications of these hydrogels. Furthermore, it discusses the current challenges and potential avenues for future development and practical implementation of ...
Ning Li   +6 more
wiley   +1 more source

Pharmacokinetics, Bioavailability, and Swallowing Safety With Riluzole Oral Film

open access: yesClinical Pharmacology in Drug Development, Volume 12, Issue 1, Page 57-64, January 2023., 2023
Abstract Dysphagia is highly prevalent in patients with amyotrophic lateral sclerosis (ALS). Riluzole is a US Food and Drug Administration‐approved treatment for ALS. Riluzole oral film (ROF; Exservan™) contains riluzole in a polymer‐based film matrix.
James Wymer   +3 more
wiley   +1 more source

THE ELECTROCARDIOGRAM IN PECTUS EXCAVATUM [PDF]

open access: bronze, 1958
José Martins de Oliveira   +2 more
openalex   +1 more source

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