Results 211 to 220 of about 326,761 (272)

Assessment of Pharmacokinetic Drug Interaction of Asciminib with Atorvastatin in Healthy Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Asciminib is the first BCR::ABL1 inhibitor that Specifically Targets the ABL Myristoyl Pocket (STAMP) in patients with chronic myeloid leukemia. This phase 1, two‐treatment‐period, drug‐drug interaction study evaluated the effect of steady‐state asciminib on the pharmacokinetics of atorvastatin.
Matthias Hoch   +9 more
wiley   +1 more source

Electrocardiogram Monitoring.

open access: yesIndian Journal of Anaesthesia, 2002
P K Dash
doaj  

Predicting Occlusion Myocardial Infarctions in the Emergency Department Using Artificial Intelligence. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Nyström A   +7 more
europepmc   +1 more source

Evaluation of clinical cardiac safety of zilurgisertib, an activin receptor‐like kinase‐2 (ALK2) inhibitor, in healthy participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract The oral, small molecule inhibitor of activin receptor‐like kinase‐2, zilurgisertib (INCB000928), is under evaluation in fibrodysplasia ossificans progressiva. Cardiac safety was assessed using electrocardiogram (ECG) parameters and a plasma concentration‐heart rate‐corrected QT (C‐QTc) interval analysis of pooled data from single ascending ...
Yan‐ou Yang   +5 more
wiley   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye   +8 more
wiley   +1 more source

A narrative review of electrocardiogram manifestation of myocardial infarction with non-obstructive coronary arteries (MINOCA). [PDF]

open access: yesJ Thorac Dis
Raul A   +9 more
europepmc   +1 more source

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