Results 241 to 250 of about 337,841 (333)

Less Symptom Improvement in Patients Undergoing TAVI With Concomitant COPD, Atrial Fibrillation and Heart Failure

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Comorbidities like a history of chronic obstructive pulmonary disease (COPD), atrial fibrillation (AF) and heart failure (HF) can cause similar symptoms as aortic stenosis (AS). However, how they influence symptom improvement and long‐term outcomes after transcatheter aortic valve implantation (TAVI) is unclear.
Kees H. van Bergeijk   +21 more
wiley   +1 more source

Comparison of Latest Generation Intra‐ and Supra‐Annular Self‐Expanding Transcatheter Heart Valves for Aortic Valve‐in‐Valve Procedures

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Valve‐in‐valve (ViV) procedures are an established therapy. Self‐expanding (SE) supra‐annular transcatheter heart valves (THV) achieve superior hemodynamics compared to balloon‐expandable (BE) intra‐annular THV, but influence of stent design versus valve position remains unclear. Aims This study compares SE intra?
Antonia Katharina Stötzel   +9 more
wiley   +1 more source

Validation for the Diagnostic Use of the HEART Score in Patients With Acute Chest Pain in Japan. [PDF]

open access: yesCirc Rep
Nomura S   +16 more
europepmc   +1 more source

Delayed Neuropsychiatric Syndrome Due to Unrecognized Carbon Monoxide Toxicity: A Case Report

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Carbon monoxide (CO) is a leading cause of poison‐related deaths in children and frequently results in nonspecific neurological symptoms and imaging findings. Rarely, pediatric patients develop a delayed neuropsychiatric syndrome (DNS) following a lucid interval.
Alexandria Valdrighi   +3 more
wiley   +1 more source

Pharmacokinetics and Safety Evaluation of a New Generic Sitafloxacin: A Phase I Bioequivalence Study in Healthy Chinese Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Sitafloxacin is a new antibiotic drug belonging to the fourth generation quinolone antibiotics. The aim of this study was to evaluate the pharmacokinetics (PK), safety profiles, and bioequivalence of test and reference 50‐mg sitafloxacin tablets under fasting and fed conditions.
Yongfang Lei   +13 more
wiley   +1 more source

Evaluation of Potential Effects of CYP3A Inhibition and CYP3A Induction on the Pharmacokinetics of Fruquintinib in Healthy Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Cytochrome P450 (CYP) 3A plays a significant role in fruquintinib metabolism in vitro. This 2‐part, 2‐period fixed‐sequence study investigated the impact of CYP3A inhibition (itraconazole) and CYP3A induction (rifampin) on the pharmacokinetics (PK) of fruquintinib and M11, its main metabolite.
Martha Gonzalez   +5 more
wiley   +1 more source

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