Results 211 to 220 of about 706,275 (282)

Low‐Frequency Noise and Stability in Electrolyte‐Gated Nanoscale Silicon Field‐Effect Transistor Sensors

open access: yesSmall Methods, EarlyView.
Electrolyte‐gated nanoscale silicon field‐effect transistor sensors provide exceptional charge sensitivity and direct electrical readout. However, their sensing accuracy is fundamentally limited by low‐frequency noise and baseline drift. This review examines the origins of noise and drift in these sensors, summarizes the key mitigation strategies, and ...
Yingtao Yu   +5 more
wiley   +1 more source

Strategies for enhancing sensitivity in lateral flow assays

open access: yesVIEW, EarlyView.
Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed   +3 more
wiley   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

open access: yesVIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi   +5 more
wiley   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

open access: yesThe FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas   +4 more
wiley   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi   +10 more
wiley   +1 more source

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