Results 41 to 50 of about 469,870 (292)

A rare case of tined lead migration of InterStim device into the rectum with subsequent novel combined surgical-endoscopic removal technique

Urology Research and Practice, 2020
After the introduction of self-anchoring tined leads in 2002, lead migration after sacral neuromodulation (SNM) in the form of InterStimTM (Medtronic, Minneapolis, MN) has been reduced; however, it remains a considerable complication of this otherwise ...
Leonidas Karapanos, Seung-Hun Chon, Ruud Kokx, Maximilian Schmautz, Axel Heidenreich   +4 more
doaj   +1 more source

Minimal Tissue Reaction after Chronic Subdural Electrode Implantation for Fully Implantable Brain–Machine Interfaces

Sensors, 2020
There is a growing interest in the use of electrocorticographic (ECoG) signals in brain–machine interfaces (BMIs). However, there is still a lack of studies involving the long-term evaluation of the tissue response related to electrode implantation. Here,
Tianfang Yan, Seiji Kameda, Katsuyoshi Suzuki, Taro Kaiju, Masato Inoue, Takafumi Suzuki, Masayuki Hirata   +6 more
doaj   +1 more source

Safety of localizing epilepsy monitoring intracranial electroencephalograph electrodes using MRI: radiofrequency-induced heating [PDF]

, 2008
Purpose: To investigate heating during postimplantation localization of intracranial electroencephalograph (EEG) electrodes by MRI. Materials and Methods: A phantom patient with a realistic arrangement of electrodes was used to simulate tissue ...
Lemieux, L., Thornton, J.S., Carmichael, D.W., Rodionov, R., McEvoy, A., Thornton, R., Allen, P.J.   +6 more
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Functional MRI with active, fully implanted, deep brain stimulation systems: Safety and experimental confounds [PDF]

, 2007
We investigated safety issues and potential experimental confounds when performing functional magnetic resonance imaging (fMRI) investigations in human subjects with fully implanted, active, deep brain stimulation (DBS) systems.
Lemieux, L., Thornton, John, Yousry, Tarek, Thobois, S., Pinto, Serge, Allen, P.J., Lemieux, Louis, Carmichael, David, Limousin-Dowsey, Patricia, Pinto, S., Limousin-Dowsey, P., Thornton, J.S., Thobois, Stéphane, Carmichael, D.W., Yousry, T., Allen, Philip   +15 more
core  

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Early Deformation of Deep Brain Stimulation Electrodes Following Surgical Implantation: Intracranial, Brain, and Electrode Mechanics

Frontiers in Bioengineering and Biotechnology, 2021
IntroductionAlthough deep brain stimulation is nowadays performed worldwide, the biomechanical aspects of electrode implantation received little attention, mainly as physicians focused on the medical aspects, such as the optimal indication of the ...
Frédéric Chapelle, Frédéric Chapelle, Lucie Manciet, Lucie Manciet, Bruno Pereira, Anna Sontheimer, Anna Sontheimer, Jérôme Coste, Jérôme Coste, Youssef El Ouadih, Youssef El Ouadih, Ruxandra Cimpeanu, Dimitri Gouot, Dimitri Gouot, Yuri Lapusta, Yuri Lapusta, Béatrice Claise, Béatrice Claise, Valérie Sautou, Yassine Bouattour, Ana Marques, Ana Marques, Adrien Wohrer, Jean-Jacques Lemaire, Jean-Jacques Lemaire   +24 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Stable, three degree-of-freedom myoelectric prosthetic control via chronic bipolar intramuscular electrodes: a case study

Journal of NeuroEngineering and Rehabilitation, 2019
Background Modern prosthetic hands are typically controlled using skin surface electromyographic signals (EMG) from remaining muscles in the residual limb.
Hendrik Adriaan Dewald, Platon Lukyanenko, Joris M. Lambrecht, James Robert Anderson, Dustin J. Tyler, Robert F. Kirsch, Matthew R. Williams   +6 more
doaj   +1 more source

Investigating the Effect of Inclination Angle and the Influence of Scan Parameters on the Appearance and Thermal and Mechanical Properties of Filigree Tension Rods of LPBF‐Manufactured NiTi Shape‐Memory Alloys

Advanced Engineering Materials, EarlyView.
This article investigates the dependence of the properties on the manufacturing orientation in the form of the inclination angle to the build plate of LPBF‐fabricated NiTi rods with a diameter of 150–220 µm. Metallographic, chemical, thermal, and mechanical characterization show behavior under identical manufacturing conditions that ranges from ...
Sandra Herzig, Michael Werner, Christian Rotsch   +2 more
wiley   +1 more source