Results 101 to 110 of about 469,870 (292)

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Identification of a First Order Model of Implanted Electrodes on the First SUAW Patient

, 2002
International audienceImpedance evaluation of implanted electrodes is necessary to ensure that the implant can deliver the specified current, and to survey any failure due to the electrodes.
Guiraud, David, Divoux, Jean-Louis, Rabischong, Pierre   +2 more
core   +3 more sources

Modeling for neurosurgical laser interstitial thermal therapy with and without intracranial recording electrodes

Current Research in Neurobiology
Laser thermal ablation has become a prominent neurosurgical treatment approach, but in epilepsy patients it cannot currently be safely implemented with intracranial recording electrodes that are used to study interictal or epileptiform activity. There is
Daniel W. Keefe, David T. Christianson, Greyson W. Davis, Hiroyuki Oya, Matthew A. Howard, III, Christopher I. Petkov, Fatima Toor   +6 more
doaj   +1 more source

Anatomy of Deja Vu in Temporal Lobe Epilepsy

Pediatric Neurology Briefs, 1994
Sixteen patients, ages 16 to 32 years, implanted with depth electrodes at Hopital Saint-Anne, Paris, France, had experienced a dreamy state (deja-vu - deja vecu, memories of complete scenes, or vague reminiscence) during sterotactic EEG (SEEG).
J Gordon Millichap
doaj   +1 more source

An investigation into the effect of fabrication parameter variation on the characteristics of screen printed thick film silver/silver chloride reference electrodes [PDF]

, 2011
Purpose – the purpose of this paper is to show how the fabrication parameters of screen-printed thick-film reference electrodes have been experimentally varied and their effect on device characteristics investigated.Design/methodology/approach – the ...
J.K. Atkinson, Glanc, M., Sophocleous, M., Garcia-Breijo, Eduardo, Garcia-Breijo, E., Atkinson, J. K., M. Glanc, M. Sophocleous, E. Garcia‐Breijo, Boltryk, P., P. Boltryk   +10 more
core   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Ion-implanted compliant electrodes for mm-size dielectric elastomer actuators [PDF]

The miniaturization of dielectric elastomer actuators requires compliant electrodes that are clean, reliable, and that can be easily patterned on a mm or μm scale.
Dubois, P, Niklaus, M, Shea, H, Rosset, S   +3 more
core   +1 more source

Fabrication, Characterization, and Functionalization of Dual Carbon Electrodes as Probes for Scanning Electrochemical Microscopy (SECM) [PDF]

, 2013
Dual carbon electrodes (DCEs) are quickly, easily, and cheaply fabricated by depositing pyrolytic carbon into a quartz theta nanopipet. The size of DCEs can be controlled by adjusting the pulling parameters used to make the nanopipet.
Korchev, Yuri E., Takahashi, Yasufumi, Paulose Nadappuram, Binoy, Actis, P, McKelvey, Kim, Unwin, Patrick R., Robinson, C, Matsue, T, Robinson, Colin, Nadappuram, Binoy Paulose, Unwin, PR, McKelvey, Kim M. (Kim Martin), Nadappuram, BP, Takahashi, Y, Matsue, Tomokazu, McKelvey, K, Actis, Paolo, Korchev, YE   +17 more
core   +1 more source

A Novel Drug‐Loaded Porous Parylene Electrode for Targeted Anti‐Inflammatory Therapy and Hearing Preservation in Cochlear Implantation

Advanced Healthcare Materials, EarlyView.
A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang, Ying‐Chang Lu, Yu‐Ming Chang, Yen‐Hui Chan, Hong‐Yu Yan, Yi‐Shan Lee, Pei‐Hsuan Lin, Cheng‐Yu Hsieh, Chuan‐Jen Hsu, Tien‐Chen Liu, Hsien‐Yeh Chen, Chen‐Chi Wu   +11 more
wiley   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source