Results 51 to 60 of about 53,308 (266)

A MCC950 analogue inflammasome inhibitor reduces the foreign body reaction against neural implants

European Journal of Medicinal Chemistry Reports
Devices implanted in the body provoke a foreign body reaction (FBR) that results in tissue encapsulation of the device and hampers its functionality over time.
Jose Crugeiras, Chiara Bisquoli, María Rodríguez-Brañas, Bruno Rodríguez-Meana, Tiziano De Ventura, Neus Hernández, Jessica Jaramillo, Alice Honovich, Ignacio Delgado-Martínez, Natalia Lago, Hanna Karlsson-Fernberg, Maria Asplund, Stefano Carli, Claudio Trapella, Giulia Turrin, Xavier Navarro   +15 more
doaj   +1 more source

Fully Additive Vertical Organic Electrochemical Transistors on Renewable and Compostable Substrates Enable Ultrasensitive Bioelectronics

Advanced Functional Materials, EarlyView.
Fully additive vertical organic electrochemical transistors (vOECTs) with channel‐length of 226 nm on a 50 µm compostable substrate achieve >106 current modulation and ∼36 mS transconductance. Ion‐selective integration enables 1.1 mA dec−1 sensitivity and 36 µm detection limit, highlighting a scalable platform for sustainable electronics and ...
Giulia Frusconi, Samuele Lavelli, Zsolt M. Kovács‐Vajna, Fabrizio Torricelli   +3 more
wiley   +1 more source

Intracranial direct electrical mapping reveals the functional architecture of the human basal ganglia

Communications Biology, 2022
Direct electrical stimulation of the basal ganglia using implanted SEEG electrodes produced a variety of motor and non-motor effects in human participants, providing insight into the functional architecture of this key brain region.
Lei Qi, Cuiping Xu, Xueyuan Wang, Jialin Du, Quansheng He, Di Wu, Xiaopeng Wang, Guangyuan Jin, Qiao Wang, Jia Chen, Di Wang, Huaqiang Zhang, Xiaohua Zhang, Penghu Wei, Yongzhi Shan, Zaixu Cui, Yuping Wang, Yousheng Shu, Guoguang Zhao, Tao Yu, Liankun Ren   +20 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Electrospun Wood‐Derived Biopolymers as Electrodes in Electrochemical Energy Storage Technologies

Advanced Functional Materials, EarlyView.
Electrospinning transforms wood‐derived cellulose and lignin into architecturally defined, binder‐free carbon electrodes with tuneable porosity and functionality. This review shows how fibre design enables decoupled charge and mass transport, enhancing performance across battery systems, while identifying key challenges in spinnability, scalability ...
Michael W. Thielke, Hattie R. Chisnall, Jesus Vazquez Chavez, Ana B. Jorge Sobrido   +3 more
wiley   +1 more source

Refining Planning for Stereoelectroencephalography: A Prospective Validation of Spatial Priors for Computer-Assisted Planning With Application of Dynamic Learning

Frontiers in Neurology, 2020
Objective: Stereoelectroencephalography (SEEG) is a procedure in which many electrodes are stereotactically implanted within different regions of the brain to estimate the epileptogenic zone in patients with drug-refractory focal epilepsy.
Vejay N. Vakharia, Vejay N. Vakharia, Vejay N. Vakharia, Rachel E. Sparks, Alejandro Granados, Anna Miserocchi, Anna Miserocchi, Anna Miserocchi, Andrew W. McEvoy, Andrew W. McEvoy, Andrew W. McEvoy, Sebastien Ourselin, John S. Duncan, John S. Duncan, John S. Duncan   +14 more
doaj   +1 more source

Implantable Ionic Memristors Based on Natural Polymer Heterojunctions

Advanced Functional Materials, EarlyView.
We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee, Byung Ik Park, Gihyeon Yim, Hyunjae Yoo, Sangjun Ma, Jundong Park, Jeong‐Yun Sun   +6 more
wiley   +1 more source

First-in-human implementation of a bidirectional somatosensory neuroprosthetic system with wireless communication

Journal of NeuroEngineering and Rehabilitation
Background Limitations in upper limb prosthesis function and lack of sensory feedback are major contributors to high prosthesis abandonment rates. Peripheral nerve stimulation and intramuscular recording can restore touch and relay motor intentions for ...
Sedona R. Cady, Joris M. Lambrecht, Karina T. Dsouza, Jeremy L. Dunning, J. Robert Anderson, Kevin J. Malone, Kyle J. Chepla, Emily L. Graczyk, Dustin J. Tyler   +8 more
doaj   +1 more source

Using Compound Neural Action Potentials for Functional Validation of a High-Density Intraneural Interface: A Preliminary Study

Micromachines
Compound nerve action potentials (CNAPs) were used as a metric to assess the stimulation performance of a novel high-density, transverse, intrafascicular electrode in rat models.
Aritra Kundu, Erin Patrick, Seth Currlin, Ryan Madler, Francisco Delgado, Ahmed Fahmy, Rik Verplancke, Marco Ballini, Dries Braeken, Maaike Op de Beeck, Nima Maghari, Kevin J. Otto, Rizwan Bashirullah   +12 more
doaj   +1 more source

Ultraflexible Neural Electrodes for Long-Lasting Intracortical Recording

iScience, 2020
Summary: Implanted electrodes provide one of the most important neurotechniques for fundamental and translational neurosciences by permitting time-resolved electrical detection of individual neurons in vivo.
Fei He, Roy Lycke, Mehran Ganji, Chong Xie, Lan Luan   +4 more
doaj   +1 more source