Results 101 to 110 of about 95,322 (257)

Listening across frequencies: Capturing seizures of all patients to advance antiseizure medication development

Epilepsia, EarlyView.
Abstract Seizure frequency has been the primary endpoint in epilepsy trials, with enrollment usually requiring ≥4 seizures per month. This threshold is more and more misaligned with clinical reality, as the availability of more treatment options has reduced baseline seizure burden, with a risk of excluding a proportion of patients from trials. Although
Stéphane Auvin, Jacqueline French
wiley   +1 more source

Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy

Epilepsia, EarlyView.
Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve, Aaron F. Struck, Dillon Scott, Richard Chappell, Andrew T. Knox   +4 more
wiley   +1 more source

Low diagnostic yield of presurgical genetic testing in adult patients with epilepsy

Epilepsia, EarlyView.
Abstract Objective To determine the diagnostic yield of genetic testing in patients undergoing presurgical evaluation for epilepsy. Methods We conducted a cohort study including 115 adult patients who underwent presurgical evaluation in the Calgary Epilepsy Program between 2019 and 2023 and who had undergone research exome sequencing.
Clara Jünemann, Amanda Stuart, Navprabhjot Kaur, Samuel Wiebe, Nathalie Jette, Shaily Singh, Felippe Borlot, Susanne Knake, The Calgary Comprehensive Epilepsy Program Collaborators, Paolo Federico, Colin Josephson, William Murphy, Andrea Salmon, Guillermo Delgado Garcia, Walter Hader, Ping Yee Billie Au, Karl Martin Klein   +16 more
wiley   +1 more source

Seizure relapse in new onset epilepsy: It is not always drug resistance

Epilepsia, EarlyView.
Abstract Objective Seizure recurrence in new onset epilepsy (NOE) can result from various factors. Although drug ineffectiveness is frequently investigated, other causes—such as nonadherence, inadequate treatment, nonepileptic events (e.g., functional/dissociative), or acute symptomatic seizures—also impact patient outcomes.
Cecilia Catania, Eric Menetre, Aikaterini Fitsiori, Felix Tobias Kurz, Gabriela Moreno Legast, Serge Vulliemoz, Mathieu Genoud, Pierre Mégevand, Roland Wiest, Fabienne Picard, Sandor Beniczky, Margitta Seeck   +11 more
wiley   +1 more source

Long‐term prognosis of pharmacotherapy in newly diagnosed focal epilepsy patients and the predictive value of baseline seizure timing: A prospective cohort study

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun, Shouye Sun, Xinyue Zhang, Weihong Lin   +3 more
wiley   +1 more source

Complete seizure freedom following minimally invasive laser callosotomy in a patient with lissencephaly type 1: Challenging the traditional paradigm

Epileptic Disorders, EarlyView.
Agilda Dema, Archie Baskaran, Joshua Chang, Douglas Nordli III, Peter Warnke   +4 more
wiley   +1 more source

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Tai Chi, brain activity and psychological outcomes: a systematic scoping review. [PDF]

Front Psychol
Yue F, Chen N, He H, Zhang X, Pan C, Yang H.   +5 more
europepmc   +1 more source

Pediatric epilepsy surgery: Global survey of referral and presurgical evaluation practices

Epilepsia, EarlyView.
Abstract Objective Pediatric epilepsy surgery is well established, but contemporary global data on referral and presurgical evaluation practices are lacking. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Task Force study provides an updated overview of current trends and regional differences. Methods Group‐level data were
Georgia Ramantani, J. Helen Cross, Dorottya Cserpan, Emtnan Ahemad, Javier Aparicio, Alexis Arzimanoglou, Carmen Barba, William Bingaman, Kees Braun, Richard J. Burman, James Butler, Lixin Cai, Dezhi Cao, Roberto Caraballo, Mathilde Chipaux‐Raffo, Thomas Cloppenborg, Arthur Cukiert, Cristine Mella Cukiert, Sameer Dal, Dario Englot, Noelle Enright, Aria Fallah, Sarah Ferrand Sorbets, Martha Feucht, Deepak Gill, Laura Guio Mahecha, Aris Hadjinicolaou, Tove Hallböök, A. Simon Harvey, Hans Holthausen, Yuwu Jiang, Lakshminarayanan Kannan, Kalman A. Katlowitz, Katarzyna Kotulska‐Jóźwiak, Martin Kudr, Matt Lallas, Ahsan Moosa Naduvil Valappil, Sandeep Bhagwan Patil, Tom Pieper, Nicola Specchio, Manjari Tripathi, Lejla Vendegh, Howard Weiner, Jo Wilmshurst, Mary Lou Smith, Elaine Wirrell, ILAE Pediatric Epilepsy Surgery Task Force and Study Group, Fabrice Bartolomei, Juan Carlos Benedetti Isaac, Poodipedi Sarat Chandra, Mary Connoly, Daniel Curry, Vicki Deli‐Peri, Luca De Palma, Nabeel Diab, Petia Dimova, Carolina Munoz Castro, Georg Dorfmüller, Jana Domínguez, Gianluca D'Onofrio, Christin Eltze, Johannes M. Nico Enslin, András Fogarasi, Siby Gopinath, Renzo Guerrini, Giulia Nobile, Masaki Iwasaki, Sita Jayalakshmi, Takayuki Kikuchi, Noritsugu Kunihiro, Paweł Kowalczyk, Niklaus Krayenbühl, Pavel Kršek, Thilo Kalbhenn, Kensuke Kawai, Cassia Maniquis, Wim Otte, María Ángeles Pérez‐Jiménez, Juan Carlos Pérez‐Poveda, Catherine Riney, Jonathan Roth, Sabine Rona, Karl Rössler, Olga Teo, Oana Tarta Arsene, Laura Tassi, Hartlieb Till, T S Dhanya, Catalina Soto Órdenes, Piradee Suwanpakdee, Steffen Syrbe, Nigel Peter Symss, Jay Shetty, Dilşad Türkdoğan, Takehiro Uda, Naotaka Usui, Vrajesh Udani, Jithangi Wanigasinghe, Yi Wang   +98 more
wiley   +1 more source

Electroencephalography Today [PDF]

Journal of the Royal Society of Medicine, 1978
  +11 more sources