Results 191 to 200 of about 141,546 (297)

How much does the reduced electroencephalographic montage matter for seizure detection? A large‐cohort simulation study

open access: yesEpilepsia, EarlyView.
Abstract Objective Subscalp electroencephalographic (EEG) systems with few channels have emerged as promising solutions for ultra‐long‐term seizure monitoring, but the impact of montage configuration on automated seizure detection is unclear. We compared automated detection performance between full‐scalp and simulated reduced montages approximating ...
Joe Kojima   +8 more
wiley   +1 more source

Scn1a‐mediated developmental regulation of prefrontal cortex plasticity and cognition

open access: yesEpilepsia, EarlyView.
Abstract Objective The voltage‐gated sodium channel Nav1.1, encoded by Scn1a, is essential for γ‐aminobutyric acid (GABA)ergic function, and its alteration is associated with neurological disorders such as Dravet syndrome and Alzheimer's disease. We previously demonstrated that local Nav1.1 dysfunction in the medial prefrontal cortex (mPFC) during ...
Maurizio S. Riga   +5 more
wiley   +1 more source

Prevalence of epilepsy and the burden of underlying causes: Canadian validation of Danish estimates

open access: yesEpilepsia, EarlyView.
Abstract Objective Recent work has provided population‐based estimates of the prevalence of cause‐specific epilepsy across the lifespan in Denmark. We sought to externally validate these Danish “secondary epilepsy” findings to ascertain consistency across geographic regions.
Marin Anderson   +6 more
wiley   +1 more source

Classifying seizures in practice: Testing the 2025 ILAE framework among clinicians in South Africa

open access: yesEpilepsia, EarlyView.
Abstract Objective The 2025 International League Against Epilepsy (ILAE) seizure classification introduced a basic version for nonspecialists, but its usability is untested. We evaluated whether a multidisciplinary frontline workforce in South Africa could apply it, how consistently, and whether performance improved after self‐directed exposure ...
Aayesha J. Soni   +13 more
wiley   +1 more source

Interictal epileptiform discharges on scalp electroencephalography: Reproducibility of visual interpretation—A systematic review

open access: yesEpilepsia, EarlyView.
Abstract Objective Interictal epileptiform discharges (IEDs) are a key diagnostic finding in first seizure, early epilepsy, and acute brain dysfunction. Variability in visual electroencephalographic (EEG) analysis contributes to diagnostic uncertainty. We performed a systematic review of the reproducibility of IED detection in clinical EEG.
Jan Brogger   +4 more
wiley   +1 more source

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