Results 211 to 220 of about 96,332 (312)

WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse

open access: yesEpilepsia, EarlyView.
Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper   +11 more
wiley   +1 more source

New onset refractory status epilepticus (NORSE) versus refractory status epilepticus not meeting NORSE criteria: A comparative clinical and electroencephalography‐based study

open access: yesEpilepsia, EarlyView.
Abstract Objective New onset refractory status epilepticus (NORSE) is a rare, severe presentation of refractory status epilepticus (RSE), with approximately half of cases cryptogenic NORSE (c‐NORSE). We compared electroencephalographic (EEG) findings alongside clinical features between NORSE and RSE not meeting NORSE criteria to better understand ...
Seren Hawksworth   +6 more
wiley   +1 more source

Can electroencephalography (EEG) identify the different dimensions of pain in fibromyalgia? A pilot study. [PDF]

open access: yesBMC Musculoskelet Disord
Diniz L   +9 more
europepmc   +1 more source

Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber   +13 more
wiley   +1 more source

Electroencephalography (EEG) for Neurological Prognostication in Post-Anoxic Coma Following Cardiac Arrest and Its Relationship to Outcome. [PDF]

open access: yesBrain Sci
Shivji Z   +8 more
europepmc   +1 more source

Ventral anterior thalamic dysfunction distinguishes seizure generalization in temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal‐to‐bilateral tonic–clonic seizures (FBTCS) in temporal lobe epilepsy (TLE) involve thalamocortical networks, yet the functional integrity and role of specific thalamic subregions in seizure generalization remain unclear. In this cross‐sectional study, we investigated whether thalamic subregion functional connectivity patterns ...
Stacy N. Hudgins   +3 more
wiley   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta   +26 more
wiley   +1 more source

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