Results 61 to 70 of about 3,257,003 (296)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Collision of a Positron with the Capture of an Electron from Lithium and the Effect of a Magnetic Field on the Particles Balance

Chemosensors, 2021
The processes of scattering slow positrons with the possible formation of positronium play an important role in the diagnosis of both composite materials, including semiconductor materials, and for the analysis of images obtained by positron tomography ...
Elena V. Orlenko, Alexandr V. Evstafev, Fedor E. Orlenko   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Flagellar Motility and Structure in the Hyperthermoacidophilic Archaeon Sulfolobus solfataricus [PDF]

, 2007
Flagellation in archaea is widespread and is involved in swimming motility. Here, we demonstrate that the structural flagellin gene from the crenarchaeaon Sulfolobus solfataricus is highly expressed in stationary-phase-grown cells and under unfavorable ...
Szabó, Zalán,, Blum, Paul, Groeneveld, Maarten,, Sani, Musa,, Driessen, Arnold J. M., Albers, Sonja-Verena,, Zolghadr, Behnam, Zolghadr, Benham,, Albers, Sonja-Verena, Boekema, Egbert J.,, Albers, Sonja Verena, Groeneveld, Maarten, Blum, Paul,, Schelert, James, Sani, Musa, Szabo, Zalan, Zolghadr, Benham, Schelert, James,, Boekema, Egbert J., Driessen, Arnold J.M.,   +19 more
core   +2 more sources

‘Twisted’ electrons

Contemporary Physics, 2018
Electrons have played a significant role in the development of many fields of physics during the last century. The interest surrounding them mostly involved their wave-like features prescribed by the quantum theory. In particular, these features correctly predict the behaviour of electrons in various physical systems including atoms, molecules, solid ...
Hugo Larocque, Ido Kaminer, Vincenzo Grillo, Gerd Leuchs, Miles J Padgett, Robert W Boyd, Mordechai Segev, Ebrahim Karimi   +7 more
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

S-wave model in electron-atom collisions [PDF]

, 2004
This thesis discusses the theory and presents the numerical solution of the S-wave models of electron-hydrogen and electron-helium scattering. The Convergent Close-Coupling (CCC) method is used to obtain the numerical results.
Plottke, Christopher Martin
core  

Comparison of Megavoltage Electron Dosimetry Beams in Radiation Therapy Using Different Protocols [PDF]

Journal of Kerman University of Medical Sciences
Background: International Atomic Energy Agency (IAEA) and American Association of physicist in Medicine (AAPM) have introduced new protocols for dosimetry of electron and photon megavoltage beams and increased them to more than five protocols at the ...
Zahra Jomehzadeh, Ali Jomehzadeh
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source