Results 51 to 60 of about 878,894 (294)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Misconceptions associated with the origin of charge density waves

Advances in Physics: X, 2017
Charge density wave (CDW) is an important concept in condensed matter physics, germane to a number of physical phenomena. But the origin of CDW is still under debate, partly because the origin and properties of CDW are highly material-dependent.
Xuetao Zhu, Jiandong Guo, Jiandi Zhang, E. W. Plummer   +3 more
doaj   +1 more source

A low-disorder Metal-Oxide-Silicon double quantum dot

, 2018
One of the biggest challenges impeding the progress of Metal-Oxide-Silicon (MOS) quantum dot devices is the presence of disorder at the Si/SiO$_2$ interface which interferes with controllably confining single and few electrons.
Hazard, Thomas M., Houck, Andrew A., Kim, Jin-Sung, Lyon, Stephen A.   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The Ancient Romans’ Route to Charge Density Waves in Cuprates

Condensed Matter, 2019
An account is given of the main steps that led the research group in Rome, to which the author belongs, to the formulation of the charge-density-wave scenario for high- T c superconducting cuprates.
Sergio Caprara
doaj   +1 more source

Simulation of Charge-Equilibration and Acceleration of Solar Energetic Ions [PDF]

, 2000
Recent measurements of the mean ionic charge states of solar energetic iron and silicon by SAMPEX and ACE during the large solar events of 1992 November 1 and 1997 November 6 show a mean ionic charge that increases with energy.
Barghouty, A. F., Mewaldt, R. A.
core   +1 more source

Interchain coupling effects on photoinduced phase transitions between neutral and ionic phases in an extended Hubbard model with alternating potentials and an electron-lattice coupling

, 2006
Dynamics of ionic-to-neutral and neutral-to-ionic phase transitions induced by intrachain charge-transfer photoexcitations are studied in a quasi-one-dimensional extended Hubbard model with alternating potentials and an electron-lattice coupling for ...
Yonemitsu, Kenji
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The effect of transport apertures on relay-imaged, sharp-edged laser profiles in photoinjectors and the impact on electron beam properties

Journal of Synchrotron Radiation
In a photoinjector electron source, the initial transverse electron bunch properties are determined by the spatial properties of the laser beam on the photocathode.
Mark Roper, Suzanna Percival, Katherine Morrow   +2 more
doaj   +1 more source

Modelling the experimental electron density: only the synergy of various approaches can tackle the new challenges

IUCrJ, 2015
Electron density is a fundamental quantity that enables understanding of the chemical bonding in a molecule or in a solid and the chemical/physical property of a material.
Piero Macchi, Jean-Michel Gillet, Francis Taulelle, Javier Campo, Nicolas Claiser, Claude Lecomte   +5 more
doaj   +1 more source