Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
42.3:An Electron Gun with Gun Pitch Modulation(Session 42:CRT Electron Guns)
openaire +1 more source
Simultaneous lasing of Ni Kα and Cu Kα lasers from an alloy foil irradiated with an intense X-ray free-electron laser pulse. [PDF]
Inubushi Y +6 more
europepmc +1 more source
Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang +8 more
wiley +1 more source
Evaporation Characteristics of Electron Beam Gun Heated Sources
T. Nagarajan, Paul C. Baynes
doaj +1 more source
3D atomic structure determination with ultrashort-pulse MeV electron diffraction. [PDF]
Hennicke V +29 more
europepmc +1 more source
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Epidemiology, morphology, and molecular characterization of Stephanurus dentatus (Nematoda: Syngamidae) in wild boars from southwestern South Korea. [PDF]
Ahn KS +5 more
europepmc +1 more source
Design and Simulation of an Electron Optical System for Terahertz Vacuum Devices. [PDF]
Jamil MH +4 more
europepmc +1 more source
Ultrafast plasma dynamics in laser-irradiated nanowire arrays probed with an X-ray free-electron laser. [PDF]
Tanaka D +20 more
europepmc +1 more source

