Results 51 to 60 of about 1,988,867 (298)

Noise2Atom: unsupervised denoising for scanning transmission electron microscopy images

open access: yesApplied Microscopy, 2020
We propose an effective deep learning model to denoise scanning transmission electron microscopy (STEM) image series, named Noise2Atom, to map images from a source domain S $\mathcal {S}$ to a target domain C $\mathcal {C}$ , where S $\mathcal {S}$ is ...
Feng Wang   +3 more
doaj   +1 more source

Post-acquisition image based compensation for thickness variation in microscopy section series

open access: yes, 2015
Serial section Microscopy is an established method for volumetric anatomy reconstruction. Section series imaged with Electron Microscopy are currently vital for the reconstruction of the synaptic connectivity of entire animal brains such as that of ...
Bogovic, John A.   +2 more
core   +1 more source

Kikuchi ultrafast nanodiffraction in four-dimensional electron microscopy [PDF]

open access: yes, 2011
Coherent atomic motions in materials can be revealed using time-resolved X-ray and electron Bragg diffraction. Because of the size of the beam used, typically on the micron scale, the detection of nanoscale propagating waves in extended ...
A. H. Zewail   +13 more
core   +2 more sources

Immune Electron Microscopy

open access: yesExperimental Biology and Medicine, 1960
SummaryA method is described by which immune systems can be studied at subcellular level with the electron microscope, using a ferritin-antibody conjugate. A conjugated immune serum to Staphylococcus aureus was applied to homologous organisms, embedded in methacrylate with uranium and thin sections cut.
C W, SMITH   +3 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Performance evaluation of pipelines for mapping, variant calling and interval padding, for the analysis of NGS germline panels

open access: yesBMC Bioinformatics, 2021
Background Next-generation sequencing (NGS) represents a significant advancement in clinical genetics. However, its use creates several technical, data interpretation and management challenges.
Maria Zanti   +8 more
doaj   +1 more source

Attosecond electron pulses for 4D diffraction and microscopy [PDF]

open access: yes, 2007
In this contribution, we consider the advancement of ultrafast electron diffraction and microscopy to cover the attosecond time domain. The concept is centered on the compression of femtosecond electron packets to trains of 15-attosecond pulses by the ...
Baum, Peter, Zewail, Ahmed H.
core   +3 more sources

Electrostatic Electron Microscopy. III [PDF]

open access: yesJournal of Applied Physics, 1943
This article, the final one of a series on the design of electrostatic electron microscopes, contains a description of an instrument which illustrates the principles previously discussed. The microscope described is believed to be the first constructed with the object of providing the greatest of simplicity in construction, operation, and maintenance ...
Bachman, C. H., Ramo, Simon
openaire   +6 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Three-dimensional distribution of individual atoms in the channels of beryl

open access: yesCommunications Materials
Single atom detection in nanoporous materials is a significant challenge, particularly due to their sensitivity to electron irradiation. Here, natural beryl (Be3Al2Si6O18) is used as a model system to quantitatively analyse the occupancy of its atomic ...
Daniel Knez   +9 more
doaj   +1 more source

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