Results 61 to 70 of about 192,965 (309)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Electron optics in ballistic graphene [PDF]
, 2015 This thesis is centered on the experimental observation of electron-optics phenomena in graphene. In Chapter 2, graphene is introduced and the ability to form p-n junctions, with particular regard to electron optics experiments, is discussed.
Rickhaus, Peter
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Charge Carrier Dynamics in Electron-Transport-Layer-Free Perovskite Solar Cells
, 2019 Better understanding of the carrier dynamics process in electron-transport-layer (ETL)-free perovskite solar cells (PSCs) enables further exploration of the perovskite potential and corresponding device structure design.
Can Gao +15 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Low resistivity ZnO-GO electron transport layer based CH3NH3PbI3 solar cells
AIP Advances, 2016 Perovskite based solar cells have demonstrated impressive performances. Controlled environment synthesis and expensive hole transport material impede their potential commercialization.
Muhammad Imran Ahmed +5 more
doaj +1 more source
Electronic Transport Properties of Few-Layer Graphene Materials
, 2011 26 pages, 8 ...
Russo, Saverio +5 more
openaire +4 more sources
Quantum Transport of Charge Density Wave Electrons in Layered Materials
Materials Today Physics, 2023 The charge density wave (CDW) is a condensate that often forms in layered materials. It is known to carry electric current \emph{en masse}, but the transport mechanism remains poorly understood at the microscopic level. Its quantum nature is revealed by several lines of evidence.
John H. Miller +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source