Results 31 to 40 of about 601,433 (260)

Utilización de formatos abiertos en la difusión de información financiera y presupuestaria de la Administración pública local

IDP, 2008
Durante los últimos años, los autores han publicado diferentes estudios relativos a e-government y al grado de divulgación en la Red de información pública de las entidades locales. En el presente trabajo se ofrece una visión crítica del papel que juegan
Jesús García García, Ana Cárcaba García   +1 more
doaj   +1 more source

Students’ Perception towards New Face of Education during This Unprecedented Phase of COVID-19 Outbreak: An Empirical Study of Higher Educational Institutions in Saudi Arabia

European Journal of Investigation in Health, Psychology and Education, 2022
Purpose: To examine the perception of students regarding an e-learning system adopted by various educational institutions in the Kingdom of Saudi Arabia during the COVID-19 pandemic. Methodology: A web-based-survey was conducted among selected university
Mohammad Asif, Mohammed Arshad Khan, Sufyan Habib   +2 more
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Metadatos de datos abiertos : estudio de caso en Uruguay

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2015
Objetivo: analizar los metadatos de datos abiertos en boga desde la perspectiva de su adecuación a los objetivos de recuperación y uso. -- Metodología: se plantea la extensión de Data Catalog Vocabulary (DCAT) a una nueva clase que modele el nivel del ...
Temesio, Sylvana
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Electronic government and public administration [PDF]

International Review of Administrative Sciences, 2005
Electronic government encompasses all government roles and activities, shaped by information and communications technologies (ICTs). Going well beyond analogies to e-commerce, it encompasses the four domains of governance and public administration: the state’s economic and social programs; its relationships with the citizen and the rule of law (e ...
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Features of Electronic Tax Administration

Economics: time realities
The article examines the process of electronic tax administration in Ukraine, emphasizing its significance for the stability and development of the economy. It analyzes the key aspects of implementing electronic services that facilitate interaction between tax authorities and taxpayers.
Selivanova, Natalia, Kalabina, Victoria, Minzhyrian, Nadiia   +2 more
openaire   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source