Results 121 to 130 of about 1,311 (184)

Clinical application of an Asian Screening Array-based preimplantation genetic testing workflow for various genetic disorders. [PDF]

Orphanet J Rare Dis
Peng C, Ren J, Zhou F, Chen H, Yang H, Li Y, Keqie Y, Zhao X, Liu Z, Hu T, Zhang X, Ding T, Yang J, Luo S, Fan W, Chen X, Liu S.   +16 more
europepmc   +1 more source

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka, Johann Kornowski, Elena Laakmann, Barbara Schmalfeldt, Tim Zell, Glenn Geidel, Christoffer Gebhardt, Pia Roser, Volkmar Müller, Julian Kött   +9 more
wiley   +1 more source

SDC4 silencing promotes cell cycle arrest at the restriction point (R point) in anoikis-resistant endothelial cells. [PDF]

Cytotechnology
Ferreira BZF, Pereira DMC, Onyeisi JOS, Machado RS, Tamura RE, Nader HB, Lopes CC.   +6 more
europepmc   +1 more source

Effects of Concomitant Medications on Clinical and Immunological Outcomes of Cancer Patients Treated With Oncolytic Adenoviruses

International Journal of Cancer, EarlyView.
ABSTRACT Medication taken for other reasons than for the treatment of malignant disease, termed concomitant medication, is known to affect outcomes when used with immune checkpoint inhibitor therapy and other oncological drugs. However, no research in humans has addressed the relationship between concomitant medications and efficacy of oncolytic ...
Santeri A. Pakola, Tatiana V. Kudling, Nea Ojala, James H. A. Clubb, Victor Arias, Elise Jirovec, Mirte van der Heijden, Arianna Eleuteri, Lyna Haybout, Susanna Grönberg‐Vähä‐Koskela, Katriina Jalkanen, Tuomo Alanko, Matthew S. Block, Inge Marie Svane, Anna Kanerva, Otto Hemminki, Dafne C. A. Quixabeira, Claudia Kistler, Suvi Sorsa, Victor Cervera‐Carrascon, Akseli Hemminki   +20 more
wiley   +1 more source

Apoptotic vesicles from endothelial cells promote endothelial progenitor cell differentiation and angiogenesis via miR-30a-5p mediated activation of the EGFR/PI3K/AKT/VEGF pathway. [PDF]

Stem Cell Res Ther
Lei S, Zhou J, Hu X, Xie J, Wang L, Kou T, Xu L, Wang J, Cheng Y, Zhao S, Zhang T, Lu D, Chen Y, Ying Y, Xin X, Xu X, Zhang Y, Wang J, Qiu C, Cheng G, Lyu Q, Lin M, Pan Y, Cao T.   +23 more
europepmc   +1 more source

Van der Waals ferroelectric semiconductor tunnel junction with ultra‐low switching voltage

InfoMat, EarlyView.
Ferroelectric tunnel junctions are promising building blocks for energy‐efficient memory and brain‐inspired computing, but their practical use is limited by the relatively high voltages required for operation. Here, we develop an all‐two‐dimensional ferroelectric tunnel junction based on AgBiP2Se6 that enables reliable memory operation below 0.2 V and ...
Fuqin Sun, Ruihuan Duan, Ziqian Xin, Yinxiao Li, Bingyuan Xue, Zihua Tian, Kejie Guan, Fan Liu, Xiaoshuang Gou, Yingyi Wang, Weifan Zhou, Cheng Zhang, Lin Liu, Zhao Wang, Jia Shi, Zheng Liu, Xiaowei Wang, Ting Zhang   +17 more
wiley   +1 more source

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

JCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz, Leyre Gambra, Samuele Cortese, Pablo Lizoain, Diana Rodriguez‐Romero, Ursula Paiva, Carmen Gándara, Sara Magallón, Gonzalo Arrondo   +8 more
wiley   +1 more source

Peanut oral immunotherapy at a single academic medical center using a volume-based approach with store-purchased peanut products. [PDF]

J Allergy Clin Immunol Glob
Devonshire AL, Magier AZ, Wilson BE, Rosenberg C, Winslow A, Risma KA, Abonia JP, Sherenian MG, Assa'ad AH, Andorf S, Schwartz JT.   +10 more
europepmc   +1 more source

Integrating Artificial Intelligence in Periodontal Diagnosis: A Comparative Evaluation of ChatGPT‐4 and Dental Educators

Journal of Dental Education, EarlyView.
ABSTRACT Objective As artificial intelligence (AI) tools gain traction in healthcare, their role in periodontal diagnostics remains largely unexplored. This study evaluated the diagnostic accuracy of ChatGPT‐4 in applying the 2017 Classification of Periodontal and Peri‐Implant Diseases and Conditions compared to US dental school faculty, with the goal ...
Ellie Y. Ji, Kobe A. George, Zabihulla Ahmadi, Eva Bender, Matthew Finkelman, Mark Mintline, Samantha Parad, Thiago Porto, Celine C. Sheng, Aditya Tadinada, Jennifer Chang   +10 more
wiley   +1 more source