Results 181 to 190 of about 50,134 (250)

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang   +8 more
wiley   +1 more source

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang   +19 more
wiley   +1 more source

Prevalence and Mental Health Correlates of Electronic Cigarette Use Among Pediatric Primary Care Patients. [PDF]

open access: yesClin Pediatr (Phila)
Braciszewski JM   +5 more
europepmc   +1 more source

Clinical modifiers of the association between type 1 diabetes and dementia incidence

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Type 1 diabetes mellitus (T1DM) increases dementia risk. Understanding clinical modifiers of that effect could inform prevention. METHODS We analyzed data from All of Us. Participants were aged ≥50 years with T1DM (n = 5,442) or no diabetes (n = 226,819).
Anna M. Pederson   +13 more
wiley   +1 more source

Altered Neurovascular Coupling Dynamics During Dobutamine‐Induced Acute Stress

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background Neurovascular coupling (NVC) is essential for regulating brain metabolism and energy supply and may be altered under acute stress. This study aimed to investigate how acute stress induced by dobutamine affects NVC. Materials and methods This study enrolled 38 healthy participants undergoing a resting‐state fMRI scan and an arterial ...
Rui Wang   +10 more
wiley   +1 more source

Environmental Regulation at the Crossroads: A Review of Catalysts and Barriers in Circular Economy Transitions

open access: yesBusiness Strategy and the Environment, Volume 35, Issue 6, Page 8432-8447, September 2026.
ABSTRACT Amid growing resource pressures, environmental regulation plays a critical role in enabling the transition to a circular economy (CE). This study conducts a systematic literature review to synthesize how different regulatory approaches—command‐and‐control, market‐based, voluntary, and reflexive—affect CE transitions across economic and ...
Li Yuan
wiley   +1 more source

Development of a Prognostic Survival Risk Score for Lung Cancer Patients With Type 2 Diabetes Mellitus: A Territory‐Wide Retrospective Cohort Study

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Lung cancer is a leading cause of cancer‐related mortality, and its prognosis is often affected by comorbidities such as type 2 diabetes mellitus (T2DM). This study aimed to identify survival risk factors for lung cancer patients with T2DM, evaluate the predictive models, and develop a risk score system for survival prediction ...
Claire Chenwen Zhong   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy