Results 191 to 200 of about 6,699,048 (236)
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles +14 more
wiley +1 more source
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang +19 more
wiley +1 more source
Clinical modifiers of the association between type 1 diabetes and dementia incidence
Abstract INTRODUCTION Type 1 diabetes mellitus (T1DM) increases dementia risk. Understanding clinical modifiers of that effect could inform prevention. METHODS We analyzed data from All of Us. Participants were aged ≥50 years with T1DM (n = 5,442) or no diabetes (n = 226,819).
Anna M. Pederson +13 more
wiley +1 more source
Altered Neurovascular Coupling Dynamics During Dobutamine‐Induced Acute Stress
ABSTRACT Background Neurovascular coupling (NVC) is essential for regulating brain metabolism and energy supply and may be altered under acute stress. This study aimed to investigate how acute stress induced by dobutamine affects NVC. Materials and methods This study enrolled 38 healthy participants undergoing a resting‐state fMRI scan and an arterial ...
Rui Wang +10 more
wiley +1 more source
ABSTRACT Amid growing resource pressures, environmental regulation plays a critical role in enabling the transition to a circular economy (CE). This study conducts a systematic literature review to synthesize how different regulatory approaches—command‐and‐control, market‐based, voluntary, and reflexive—affect CE transitions across economic and ...
Li Yuan
wiley +1 more source
ABSTRACT Background Lung cancer is a leading cause of cancer‐related mortality, and its prognosis is often affected by comorbidities such as type 2 diabetes mellitus (T2DM). This study aimed to identify survival risk factors for lung cancer patients with T2DM, evaluate the predictive models, and develop a risk score system for survival prediction ...
Claire Chenwen Zhong +12 more
wiley +1 more source
Electronic cigarettes – where are we headed?
Andrew Loughead
doaj
ObjectiveTo introduce the otolaryngology community to the current state of research regarding electronic cigarettes, with special attention paid to mechanism, impact on health and addiction, and use in smoking cessation.Data SourcesReview of Google Scholar and PubMed databases using the keywords electronic cigarettes, e‐cigs, e‐cigarettes, and vaping ...
Hayley, Born +5 more
core +6 more sources

