Results 31 to 40 of about 7,170,318 (307)
A Review of Approaches for Predicting Drug–Drug Interactions Based on Machine Learning
Frontiers in Pharmacology, 2022 Drug–drug interactions play a vital role in drug research. However, they may also cause adverse reactions in patients, with serious consequences. Manual detection of drug–drug interactions is time-consuming and expensive, so it is urgent to use computer ...
Ke Han +10 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Editorial: How to prevent, detect and control common method variance in electronic commerce research
, 2020 In electronic commerce research, questionnaire surveys are widely used to gather information. But these questionnaires usually include scales to measure both the predictor constructs and the criterion constructs, and the data is often collected from the ...
Meseguer Artola, Antoni +3 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein +3 more
wiley +1 more source
Fractal and FractionalElectronic commerce plays a vital role in the digital age, and the creation of a good electronic commerce ecosystem is crucial to maintaining economic growth.
Jianhong Guo +2 more
doaj +1 more source
Main Issues on Electronic Commerce and Policy Recommendations
East Asian Economic Review, 1998 "Electronic Commerce" means that people sell and buy commodity, labor service and information through internet and now is mainly be used in commercial intercourse.
Chongwha Lee , Seongbong Lee
doaj +1 more source
Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study
Arthritis Care &Research, EarlyView.Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali +11 more
wiley +1 more source
A platform for electronic commerce with adaptive agents [PDF]
, 2000 Market research suggests that organisations, in general, have adifferentiation strategy when approaching Electronic Commerce. Thus, in orderto be useful, agent technology must take into account this market characteristic.When extending its application to
Henrique Lopes Cardoso +1 more
core +1 more source