Results 31 to 40 of about 294,685 (245)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Strategic Assessment in Banking Service Quality [PDF]

مطالعات مدیریت راهبردی, 2016
Electronic banking as one of the solutions for E-commerce prosperity has been constantly expanding and providing banking services through the Internet has had an unprecedented leap in recent years.
Maryam Akhavan Kharazian, Maryam Ahmadi Taheri   +1 more
doaj  

A Comparative Study of Notices in International Sale of Goods Contracts and Iranian Law [PDF]

Faṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī
This study undertakes a comparative analysis of notices in international sale of goods contracts, contrasting the structured framework of the United Nations Convention on Contracts for the International Sale of Goods (CISG, 1980) with the diverse ...
seyed mohammadjavad hosseini, Ebrahim Abdipourfard   +1 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

E-consulting of Small and Medium Agribusiness Enterprises: The case of eEurope Godigital application into the Peloponnese Region [PDF]

, 2002
This study describes the design and development of a web-based electronic training system aiming at business operations of small and medium-sized agribusiness enterprises (SMAEs). The proposed system will meet current and future needs of SMAEs for timely,
Costopoulou, C. I., Tsiligiridis, Th, Vlachos, Ilias   +2 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The application of blockchain with a comparative approach and its impact on risk, flexibility and internal control evaluation [PDF]

ارزش آفرینی در مدیریت کسب و کار
The purpose of the current research is the application of blockchain with a comparative approach of its effect on risk, flexibility and evaluation of internal control.
mohammadsadegh aminipoor, HamidReza GholamniaRoshan, azadeh kiapour, Iman Dadashi   +3 more
doaj   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

The Means Structure of Information Resources Processing in Electronic Content Commerce Systems

, 2015
Some of principal problems of electronic content commerce and functional services of content processing are analyzed in the article. Proposed method gives an opportunity to form resources processing tools for electronic commerce systems so as implement subsystems for content formation, management and support.
Vysotska, Victoria, Chyrun, Lyubomyr
openaire   +1 more source