Results 31 to 40 of about 532,089 (313)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Data-driven educational algorithms pedagogical framing

RIED: Revista Iberoamericana de Educación a Distancia, 2020
Data from students and learning practices are essential for feeding the artificial intelligence systems used in education. Recurrent data trains the algorithms so that they can be adapted to new situations, either to optimize coursework or to manage ...
Daniel Domínguez Figaredo
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Implementasi Electronic Data Processing Pada Koperasi Wanita

Eksis: Jurnal Riset Ekonomi dan Bisnis, 2017
Penelitian yang dilakukan pada Koperasi Wanita di Jombang ini bertujuan untukMengetahui sebaran Koperasi di Jombang yang menyelenggarakan pencatatan transaksi secara komputerisasi (Electronic Data Processing), mengetahui penerapan unsur-unsur Electronic ...
Rita Mutiarni
doaj   +1 more source

Scale‐wise interaction fusion and knowledge distillation network for aerial scene recognition

CAAI Transactions on Intelligence Technology, 2023
Aerial scene recognition (ASR) has attracted great attention due to its increasingly essential applications. Most of the ASR methods adopt the multi‐scale architecture because both global and local features play great roles in ASR.
Hailong Ning, Tao Lei, Mengyuan An, Hao Sun, Zhanxuan Hu, Asoke K. Nandi   +5 more
doaj   +1 more source

Method for processing electronic data

, 2021
A method for processing electronic data includes the steps of transforming the electronic data to a matrix representation including a plurality of matrices; decomposing the matrix representation into a series of matrix approximations; and processing ...
Chen, J., Zeng, W.-J., Zoubir, A. M., So, H. C.   +3 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Steered Response Power for Sound Source Localization: a tutorial review

EURASIP Journal on Audio, Speech, and Music Processing
In the last three decades, the Steered Response Power (SRP) method has been widely used for the task of Sound Source Localization (SSL), due to its satisfactory localization performance on moderately reverberant and noisy scenarios.
Eric Grinstein, Elisa Tengan, Bilgesu Çakmak, Thomas Dietzen, Leonardo Nunes, Toon van Waterschoot, Mike Brookes, Patrick A. Naylor   +7 more
doaj   +1 more source