Results 51 to 60 of about 12,929,834 (255)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

ELECTRONIC DOCUMENTS AS ELECTRONIC EVIDENCE

open access: yesInternational Journal of Law in Changing World
The development of technology has led to the fact that a large part of the disputes has transcended national borders and acquired a cross-border character.
Gergana Varbanova
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Efficient and secure electronic evidence exchange scheme for internet of things

open access: yesFrontiers in Physics
With the rapid development of information technology, Internet of Things (IoT) is profoundly impacting various fields of the socio-economic landscape, driving the transformation of traditional industries towards intelligence.
Yulong Xiao, Liang Chen
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Dual criminality in the digital age: Strengthening cross-border cooperation in cybercrime investigations [PDF]

open access: yesCyberspace Studies
Background: The principle of dual criminality, which requires an act to be criminalized in both the requesting and requested states, is a cornerstone of mutual legal assistance.
NSHIMIYIMANA Francois Regis
doaj   +1 more source

What is the evidence for harm minimisation measures in gambling venues? [PDF]

open access: yes, 2014
What techniques are currently being used for electronic gambling machine harm minimisation, and do they work? Overview The use of electronic gambling machines (EGMs) in Australia and New Zealand constitutes the largest sector of the gambling industry ...
Louise Francis   +2 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

FUNGSI BUKTI ELEKTRONIK DALAM HUKUM ACARA PIDANA PASCA PUTUSAN MAHKAMAH KONSTITUSI NOMOR 20/PUU-XIV/2016

open access: yesJurnal Ilmiah Pendidikan Pancasila dan Kewarganegaraan, 2017
: Decision of the Constitusional Court of the Republic of Indonesia Number 20/PUU-XIV/2016 has given the interpretation of the Article 5 (1), 5 (2) and 44b Law of The Republic Indonesia Number 11 of 2008 Concerning Electronic Informations and ...
Arief Heryogi   +2 more
doaj  

Blockchain as a model for granting trust in AI-mediated digital transactions

open access: yesFrontiers in Blockchain
Digital transaction law traditionally relies on centralized trust service providers. However, the emergence of blockchain and artificial intelligence introduces decentralized and autonomous transaction systems that challenge existing legal frameworks of ...
Ghazi Ayed Alghathian   +3 more
doaj   +1 more source

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