Results 231 to 240 of about 1,427,982 (292)

Using a discrete choice experiments to explore societal preferences for valuing new drugs for rare diseases. [PDF]

Orphanet J Rare Dis
Vargas C, Goodall S, Street DJ, Espinoza M, De Abreu Lourenço R.   +4 more
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Intermediate Bandgap (IB) Cu₃VS_xSe_4-x Nanocrystals as a New Class of Light Absorbing Semiconductors. [PDF]

Nanomaterials (Basel)
Sanchez Rodriguez JJ, Palchoudhury S, Huang J, Speed D, Tiukalova E, Mante G, Hachtel J, Gupta A.   +7 more
europepmc   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

Models for SARS-CoV-2 health policies: social distancing amid vaccination and virus variants. [PDF]

R Soc Open Sci
Zhang Y, Kapoor S.
europepmc   +1 more source

Designing Thermally Compatible Template‐Coating Pairs Toward Dimensionally Stable 3D Porous Carbons with Tunable Density

Advanced Functional Materials, EarlyView.
3D porous carbons with tunable density are crucial for energy storage, separations, and load‐bearing applications; however, their fabrication is often constrained by shrinkage during pyrolysis. This study optimizes and demonstrates the versatility of a template–coating pair strategy, producing materials that largely retain their shape and hierarchical ...
Adarsh Suresh, Manuela Campos, Kendrick Xie, Elektra Makris, Jonah Lovejoy, Maya El Shamsy, Chong Liu, Stuart J Rowan   +7 more
wiley   +1 more source

Palliative care experience among primary caregivers of children with cancer in low and lower-middle-income countries: a qualitative systematic review protocol. [PDF]

BMJ Open
Nawaratne S, Weerasingha Navarathnage SD, Denagamagei SS, Seneviwickrama M.   +3 more
europepmc   +1 more source

Multi‐Faceted Binder Enhancement via Slurry‐Applicable Thiol‐Ene Click Chemistry for Low‐Pressure‐Operable All‐Solid‐State Batteries

Advanced Functional Materials, EarlyView.
Cross‐linked binders with enhanced resiliencies under low operating pressures are designed via in situ thiol‐ene click reactions within slurries. Cross‐linking improves the Young's moduli and elasticities of the styrene‐butadiene rubber binders, effectively mitigating interparticle delamination within the composite cathodes induced by volumetric ...
Young Joon Park, Kyu Tae Kim, Seunggoo Jun, Jong Seok Kim, Jaehyun Yoon, Cheol Bak, Yong Min Lee, Dong Hyeon Kim, Ji Young Kim, Yoon Seok Jung   +9 more
wiley   +1 more source

Golden‐Ratio–Guided Aperiodic Architected Metamaterials with Simultaneously Enhanced Strength and Toughness

Advanced Functional Materials, EarlyView.
Guided by the golden ratio, a class of aperiodic architected metamaterials is introduced to address the intrinsic trade‐off between strength and toughness. By unifying local geometric heterogeneity with global order, the golden‐ratio‐guided aperiodic architecture promotes spatial delocalization of damage tolerence regions, leading to more tortuous ...
Junjie Deng, Xinxin Wang, Ruochao Zhao, Zhendong Li, Kai Liu, Ke Yuan, Jia An, Xinwei Li, Chee Kai Chua, Zhonggang Wang   +9 more
wiley   +1 more source