Results 181 to 190 of about 346,749 (252)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Burden, demographic patterns, and temporal trends of parotitis in Saudi Arabia, 2015-2023: a multicenter electronic health record study. [PDF]

Front Epidemiol
Saleem RA, Sukkarieh H, Alkattan RK, Bustami R, Daher S, Alhusseini N, Fakhoury R.   +6 more
europepmc   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Provider and information technology operations staff perspectives on the feasibility of writing patient-generated health data into the electronic health record. [PDF]

JAMIA Open
Saiju A, Umakanth S, Vaynrub A, Eli R, Michel A, Crew KD, Kukafka R.   +6 more
europepmc   +1 more source

Implementing an electronic medical record system: successes, failures, lessons

International Journal of Integrated Care, 2007
Anne Moen
doaj  

Deep Phenotyping of Obesity: Electronic Health Record-Based Temporal Modeling Study. [PDF]

J Med Internet Res
Ruan X, Lu S, Wang L, Wen A, Murali S, Liu H.   +5 more
europepmc   +1 more source

Development and Application of an Algorithm for Statin-Induced Myopathy Based on Electronic Health Record-Derived Structured Elements. [PDF]

Pharmacoepidemiol Drug Saf
Oni-Orisan A, Lu M, Peng JA, Krauss RM, Iribarren C, Medina MW.   +5 more
europepmc   +1 more source

Updating the Epidemiology of Blastomycosis and Histoplasmosis in the United States, Using National Electronic Health Record Data, 2013-2023. [PDF]

J Infect Dis
Bartels JGE, Camponuri SK, Snow TT, Bustamante BLM, Kane NJ, Reynolds RM, Lee A, Hoffman MA, White TC, Remais JV, Head JR.   +10 more
europepmc   +1 more source