Results 21 to 30 of about 1,579,060 (303)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Online korean skincare decision support system [PDF]
, 2017 Despite the explosive growth of electronic commerce and the rapidly increasing number of consumers who use interactive media for pre-purchase information search and online shopping, very little is known about how consumers make purchase decisions in such
Hafit, Hanayanti +3 more
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
The Obama Administration and the Press: Leak Investigations and Surveillance in Post-9/11 America [PDF]
, 2013 U.S. President Barack Obama came into office pledging open government, but he has fallen short of his promise. Journalists and transparency advocates say the White House curbs routine disclosure of information and deploys its own media to evade scrutiny ...
Leonard Downie, Jr.
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Developing key concepts for the design of hypertext for printed books [PDF]
, 2009 In the modern world, computers and interactivity are becoming an ever-increasing phenomenon, but this means that the tactile appeal of the printed book is giving way to the increasing popularity of digital interactivity. This research explores how one of
Timpany, Claire
core +2 more sources
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Library performance measurement in the digital age [PDF]
, 2011 Book synopsis: University libraries around the world have embraced the possibilities of the digital learning environment, facilitating its use and proactively seeking to develop the provision of electronic resources and services.
Conyers, A., Payne, Philip
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Pemanfataan Media dalam Memahami Realitas Sosial di Kalangan Mahasiswa UIN SGD Bandung [PDF]
, 2013 This article explores social fenomena using mass media among students of UIN Sunan Gunung Djati, Bandung. The Aim of using mass media is to reduce the gap of information between theory and social phenomena.
dulkiah, M. (moh)
core +2 more sources
Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting +12 more
wiley +1 more source
Topologically Robust Transport of Photons in a Synthetic Gauge Field [PDF]
, 2014 Electronic transport in low dimensions through a disordered medium leads to localization. The addition of gauge fields to disordered media leads to fundamental changes in the transport properties.
Faez, S. +5 more
core +3 more sources