Results 231 to 240 of about 3,058,021 (349)

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

From authorisation to clinical practice: evolution of the use of biological medicines according to the SmPC and guidelines (2006 to 2025). [PDF]

Eur J Clin Pharmacol
Penninx BMF, Hollak CEM, Tas SW, Timmers L, de Visser SJ, van Kempen ZLE.   +5 more
europepmc   +1 more source

A Disaggregation Strategy for Nanopesticide Fabrication: Investigating the Impact of Nanosizing on Pesticide Biointeractions

Advanced Science, EarlyView.
To explore the impact of nanosizing on pesticide biointeractions, a 7‐nm (average) emamectin benzoate nanopesticide without nanocarriers or surfactants is fabricated via HOAc‐mediated disaggregation. Nanosizing enhances bioactivity against Megalurothrips usitatus and Meloidogyne enterolobii and improves plant penetration.
Jiaqi Wei, Jianxin Feng, Huiting Zhu, Kunzhong Lin, Chenhan Liu, Lin Li, Zhuoyan Xiao, Daihao Huang, Rong Liu, Huipeng Pan, Lingda Zeng, Hanhong Xu   +11 more
wiley   +1 more source

Electronic Markets [PDF]

, 2013
openaire   +1 more source

Electronic Marketing in Principle and Practice

, 1984
D. R. Henderson
semanticscholar   +1 more source

Digital Marketing Tactics, Non-Compliance With the International Code of Marketing of Breastmilk Substitutes and Legal Breaches of Code-Based Legislation by the Commercial Milk Formula Industry in Central America and the Caribbean. [PDF]

Matern Child Nutr
Mazariegos M, Paz B, Álvarez L, De León JR.   +3 more
europepmc   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

Marketing awareness, professional experience, and support for e-cigarette advertising regulation among Polish legal professionals: a latent-class analysis. [PDF]

Int J Occup Med Environ Health
Zajdel K, Merecz-Sadowska A, Sadowski A, Wojtysiak P, Kaleta D.   +4 more
europepmc   +1 more source

Presentation of the marketing mix of SPO Marketing Ltd.

A záródolgozatom a marketing-mix 7P elemeit mutatta be a S.P.O Marketing Kft-n keresztül. A dolgozatban részletes bemutatásra került a gyakorlati hely története és a jelenlegi piaci helyzete a cégnek. A dolgozatban továbbá szó esik a marketing fogalmáról
Szabó, Imre
core  

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective

Advanced Science, EarlyView.
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok, Jesús Valdés‐Hernández, Varinia Bernales, Alán Aspuru‐Guzik, Alex Zhavoronkov   +4 more
wiley   +1 more source