Results 211 to 220 of about 971,076 (335)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

A cluster randomized controlled trial of an electronic medical record-based pathway for pediatric asthma in primary care in Alberta. [PDF]

CMAJ
Potestio ML, Sharpe H, Johnson DW, Grimshaw JM, Faris P, Duan QM, Pow J, Cave A.   +7 more
europepmc   +1 more source

Challenges of self-reported medical conditions and electronic medical records among members of a large military cohort [PDF]

, 2008
the Millennium Cohort Study Team, Besa Smith, Laura Chu, Tyler C. Smith, Paul J. Amoroso, Edward J. Boyko, Tomoko I. Hooper, Gary D. Gackstetter, Margaret A.K. Ryan   +8 more
openalex   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Use of an Electronic Medical Record Integrated Tool to Identify Patients at Highest Risk of Hypoglycemia. [PDF]

AACE Endocrinol Diabetes
Fenske M, Brant A, Willner M, Eastman K, Ketz J.   +4 more
europepmc   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Analgesic use and changes in renal function in patients with heart failure in a real-world setting: a descriptive study using an electronic medical record database. [PDF]

Am Heart J Plus
Ishida R, Takano T, Tokumasu H, Sato N.
europepmc   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Gender Differences in Electronic Medical Record Usage Between Plastic Surgeons at a Single Institution. [PDF]

Plast Reconstr Surg Glob Open
Tierney MG, Via EC, Wirth PJ, Israel JS.
europepmc   +1 more source

Lessons learned from the design, development, and deployment of endTB electronic medical record for MDR-TB across 16 countries

, 2017
Cathy Hewison, Safiya Arnaout, Ali Habib, Michael Rich, Uzma Khan, James Mbabazi, Helena Huerga, Megan McGuire   +7 more
openalex   +1 more source