Results 121 to 130 of about 2,528,291 (336)
Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing
Advanced Science, EarlyView.This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang +10 more
wiley +1 more source
Engineering Feasibility Study of Fire Island as a Location for a Future Correctional Facility: Final Report [PDF]
, 1986 The "Legal Factors" section appearing on page 38–50 of this report was prepared by Stephen Conn of the UAA Justice Center, School of Justice. / This report is part of the Fire Island Prison Feasibility Study, a project conducted jointly by the School
Junge, David C. +1 more
core
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that PDZK1 loss impairs ULK1‐mediated lipophagy, driving lipid droplet accumulation and sunitinib resistance in clear cell renal cell carcinoma. PDZK1 inhibits LEF1 nuclear translocation, enhancing ULK1 transcription. Pharmacological ULK1 activation resensitizes resistant tumors to sunitinib.
Xuan Qi +11 more
wiley +1 more source
Incentives for Municipal Planning towards Citizen-centric Public e-Government - Swedish empirics [PDF]
This paper offers critical aspects on this ongoing development within the Swedish municipalities with the strategic use of ICT , for the purpose to create a digital government and to making public administration more citizen-oriented, efficient, and ...
Irene Bernhard
core
Rational planning and politicians' attitudes to spending and reform: replication and extension of a survey experiment [PDF]
, 2016 The rational planning cycle of formulating strategic goals and using performance information to assess implementation is assumed to assist decision-making by politicians. Empirical evidence for this assumption is, however, scarce.
Baekgaard, Martin +3 more
core +1 more source
Advanced Science, EarlyView.Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou +22 more
wiley +1 more source
Community owned fibre optic networks - a sustainable broadband future for rural areas in Croatia? [PDF]
For a small rural community such as the city of Krk (6.000 inhabitants), the business model for a fibre roll-out is not very promising if it is based on the classical cost-benefit analysis where investments are covered by service revenue generated.
Brusic, Igor +2 more
core
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
PELAKSANAAN PENGADAAN BARANG/JASA SECARA ELEKTRONIK (E-PROCUREMENT) PADA PEMERINTAH KOTA YOGYAKARTA
Mimbar Hukum, 2011 Yogyakarta municipality is committed to improve the quality of its procurement procedures by applying electronic procurement system, which finds its standing on Mayor Regulation Nr. 13 of /2009.
Dwi Haryati +2 more
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