AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song +6 more
wiley +1 more source
Comparing perceptions of users on digital authentication through one-time passcode, fingerprint, voice recognition, PIN code, finger swipe, and authentication of choice: A cross-sectional survey. [PDF]
Bennett A, Ukwandu E.
europepmc +1 more source
Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha +2 more
wiley +1 more source
Breast cancer screening in Europe and the role of general practitioners: A 32-country comparative survey. [PDF]
Papageorgiou DI +32 more
europepmc +1 more source
Robot‐Assisted Measurement of the Critical Micelle Concentration
The study introduces (SIMO) smart integrator for manual operations, a robotic platform for precise, repeatable determination of (CMC) critical micelle concentration in surfactants. SIMO reduces standard deviation by 80% compared to manual methods. Surfactant, dye, and diluent selection, robotic protocols, and data handling are detailed.
Vincenzo Scamarcio +3 more
wiley +1 more source
Low-value medical orders: bridging the gap between concept and action in reducing healthcare waste. [PDF]
Wen J, Tao W, Yu X.
europepmc +1 more source
Smart Bioinspired Material‐Based Actuators: Current Challenges and Prospects
This work gathers, in a review style, an extensive and comprehensive literature overview on the development of autonomous actuators based on synthetic materials, bringing together valuable knowledge from several studies. Furthermore, the article identifies the fundamental principles of actuation mechanisms and defines key parameters to address the size
Alejandro Palacios +4 more
wiley +1 more source
Exploration and practice of data-driven high-quality development in smart hospitals. [PDF]
Li L, Yang C, Zhang Z, Wu Q, Cao X.
europepmc +1 more source
Bubbles Acting as Micro End‐Effectors for Dexterous Manipulation and Sensing in Aqueous Environment
Inspired by bubbles, this article proposes a low‐cost method for multifunctional manipulation and sensing using microbubbles in aqueous environments. Bubbles are easily generated in situ, enabling the safe and adaptive handling of microobjects and sensing of microforces and surface textures.
Zichen Xu, Qingsong Xu
wiley +1 more source

