Results 171 to 180 of about 26,042 (268)

Clindamycin-resistant among Staphylococcus aureus: Investigation into phenotypic and genotypic profiles. [PDF]

PLoS One
Khursheed M, Sulaiman M, Alhassan AM, Al Awad TH, Ibrahim AE, Wilson G, Abdelrahaman HA, Eltai NO.   +7 more
europepmc   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

Advanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li, Rui Wang, Wenting Luo, Hui Gu, Tianchu Huang, Qiushi Wang, Zhengwei Yuan   +6 more
wiley   +1 more source

Molecular characterization of bla_NDM and other carbapenemases genes among carbapenem-resistant Enterobacterales from community-and hospital- acquired urinary tract infections. [PDF]

BMC Infect Dis
Razaq L, Uddin F, Alhilfi WA, Alorabi M, Sohail M.   +4 more
europepmc   +1 more source

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

Advanced Science, EarlyView.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang, Tinghong Liu, Zhirong Wei, Jinshan Xu, Jiayi Han, Jiaqi Wang, Feng Zhai, Yiran Tian, Shuli Liang   +8 more
wiley   +1 more source

A strategy targeting ferroptosis for mitochondrial reprogramming and intervertebral disc degeneration therapy. [PDF]

Theranostics
Wu T, Teng Y, Song D, Yang Y, Shen H, Sun X, Chen R, Zhao L, Zhong X, Yan Q, Niu J, Ge J, Cheng L, Zou J.   +13 more
europepmc   +1 more source

Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy

Advanced Science, EarlyView.
An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang, Yongjian Zhang, Yajuan Fu, Dangjin Ke, Qi Chen, Sijie Shao, Panpan Xue, Yuanchun Chen, Xuemei Zeng, Shuangqian Yan   +9 more
wiley   +1 more source

Exploring the correlation between magnetic resonance diffusion tensor imaging (DTI) parameters and aquaporin expression and biochemical composition content in degenerative intervertebral disc nucleus pulposus tissue: a clinical experimental study. [PDF]

BMC Musculoskelet Disord
Chen S, Sun S, Wang N, Fang X, Xie L, Hu F, Xi Z.   +6 more
europepmc   +1 more source

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source

17β-estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway. [PDF]

Front Cell Dev Biol
Liu T, Li Z, Zhang W, Guo X, Liu G, Yang D, Yang S.   +6 more
europepmc   +1 more source

Disc electrophoresis of cerebrospinal fluid protein

SEIBUTSU BUTSURI KAGAKU, 1976
Hidenori Kawakita, Noriyuki Yamauchi, Ikuo Hasue   +2 more
openaire   +2 more sources