Results 41 to 50 of about 1,302,248 (295)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Effect of chitosan structure and deposition time on structural and mechanical properties of chitosan-hydroxyapatite tubular-shaped electrodeposits for biomedical applications

open access: yesPolymer Testing, 2023
Chitosan-hydroxyapatite tubular-shaped hydrogel structures have been successfully obtained by electrophoretic deposition. The deposits show great potential in the regeneration of tubular organs and tissues, in particular peripheral nerve tissue ...
Katarzyna Nawrotek   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Electrophoretic Deposition of In2O3 nanoparticles prepared by PLAL in Water [PDF]

open access: yesEngineering and Technology Journal, 2015
Indium oxide nanoparticles were prepared in water using a Laser Pulsed Ablation technique in Liquid (PLAL). The Nd:YAG laser was used as an ablation source.
Khaleel I. Hassoon
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Electrophoretic deposition of graphene-based materials: A review of materials and their applications

open access: yesJournal of Materiomics, 2018
Recently, graphene-based materials have been successfully fabricated by the electrophoretic deposition (EPD) technique and exhibited various extraordinary properties.
Yifei Ma   +4 more
doaj   +1 more source

Advancements in Nanoparticle Deposition Techniques for Diverse Substrates: A Review

open access: yesNanomaterials, 2023
Nanoparticle deposition on various substrates has gained significant attention due to the potential applications of nanoparticles in various fields.
Daniel Escorcia-Díaz   +4 more
doaj   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

open access: yesAdvanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett   +19 more
wiley   +1 more source

Alcohol induced surface charging of colloidal quantum dots for controllable electrophoretic deposition processing

open access: yesNano Research
In this work, we report alcohol induced surface charging of colloidal quantum dots for controllable electrophoretic deposition processing. By adding a fixed amount of alcohol into a preformed quantum dots solution in non-polar solvents, quantum dots can ...
Jiaming Su   +5 more
doaj   +1 more source

Green and efficient exfoliation of ReS2 and its photoelectric response based on electrophoretic deposited photoelectrodes

open access: yesMaterials & Design, 2018
Environmentally friendly synthesis and scalable photoelectrode fabrication are important for the photoelectric conversion in photocurrent generation. We find that 28% ethanol in 72% deionized water are the best mixed solvent for efficient exfoliation of ...
Xiang Xu   +7 more
doaj   +1 more source

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