Results 41 to 50 of about 767,331 (295)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Electrophoretic Protein Deposition as a Tool for In Situ Co-Crosslinking Enzyme Immobilization: An Electrochemical/Quartz Crystal Microbalance Study

open access: yesApplied Sciences, 2023
Electrophoretic deposition is a powerful tool for depositing materials onto a substrate by using an electric field; its application in biotechnological areas, namely, electrophoretic protein deposition (EPD), is the most promising for, e.g., fabricating ...
Antonio Guerrieri   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effect of chitosan structure and deposition time on structural and mechanical properties of chitosan-hydroxyapatite tubular-shaped electrodeposits for biomedical applications

open access: yesPolymer Testing, 2023
Chitosan-hydroxyapatite tubular-shaped hydrogel structures have been successfully obtained by electrophoretic deposition. The deposits show great potential in the regeneration of tubular organs and tissues, in particular peripheral nerve tissue ...
Katarzyna Nawrotek   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Electrophoretic Deposition of In2O3 nanoparticles prepared by PLAL in Water [PDF]

open access: yesEngineering and Technology Journal, 2015
Indium oxide nanoparticles were prepared in water using a Laser Pulsed Ablation technique in Liquid (PLAL). The Nd:YAG laser was used as an ablation source.
Khaleel I. Hassoon
doaj   +1 more source

Thick composite magnetoelectric films by electrophoretic deposition [PDF]

open access: yes, 2014
Electrophoretic deposition (EPD) from colloidal suspensions was utilized for the preparation of composite magneto-dielectric films on a conductive substrate.
Galassi, Carmen   +2 more
core  

Using electrophoretic deposition to identify protein charge in biological medium

open access: yes, 2011
Protein adsorption is the first step involved in establishing a suitable integration between a biomaterial and host tissue. It is therefore of highest interest to know the electric charge of proteins present in the relevant medium to be able to predict ...
Boccaccini, A.R.   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

THICK COMPOSITE MAGNETOELECTRIC FILMS PRODUCED BY ELECTROPHORETIC DEPOSITION

open access: yes, 2014
THICK COMPOSITE MAGNETOELECTRIC FILMS PRODUCED BY ELECTROPHORETIC DEPOSITION Pietro Galizia, Carlo Baldisserri, Carmen Galassi CNR-ISTEC, Italy Electrophoretic deposition (EPD) from colloidal suspensions was utilized for the preparation of composite ...
Carmen Galassi   +2 more
core   +1 more source

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