Results 211 to 220 of about 9,782 (283)

Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
The advent of organ‐on‐chip models allows closer emulation of in vivo conditions, leading to effective, less costly, and specific drugs. Although a number of membrane‐based on‐chip models exist, better emulating functional models need to be devised for organ simulations.
Tanmayee Makarand Sathe   +1 more
wiley   +1 more source

Animal and cellular models of atrial fibrillation: a review. [PDF]

open access: yesFront Cardiovasc Med
Wu Q   +8 more
europepmc   +1 more source

Changes in Spinal Neural Circuit Plasticity in a Rat Sciatic Nerve Transection Model

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Following sciatic nerve transection (SNT), corticospinal tract (CST) labeling in the lumbar gray matter remained unchanged, whereas motor neurons showed soma atrophy with reduced perisomatic vesicular glutamate transporter 1 (vGlut1) and vesicular acetylcholine transporter (vAchT) inputs.
Katsuyuki Konishi   +13 more
wiley   +1 more source

Distribution of Voltage‐Gated Sodium Channels and Scaffolding Proteins on Vestibular Calyx Ending Delineates the Axon Initial Segment

open access: yesJournal of Comparative Neurology, Volume 534, Issue 2, February 2026.
Various sodium channel isoforms and their scaffolding proteins are found in four different microdomains in vestibular calyx‐bearing afferents. These microdomains serve different purposes, analogous to the heminode, axon initial segment, and synaptic domains of other types of sensory afferents.
Anna Lysakowski   +8 more
wiley   +1 more source

Effective Connectivity Reveals Dual‐Route Mechanism of Visual Prediction Precision via Insula and Pulvinar

open access: yesHuman Brain Mapping, Volume 47, Issue 2, February 1, 2026.
Using 7‐Tesla fMRI and dynamic causal modelling (DCM), we identified a dual‐route mechanism for high‐precision predictions: direct excitatory modulation from the insula to V1, and indirect inhibitory modulation from the insula to V1 via the pulvinar.
Linzhi Tao   +5 more
wiley   +1 more source

Arrhythmogenic Implications of Inflammatory Bowel Disease: Its Mechanisms and Treatment Effects. [PDF]

open access: yesCureus
Almasri ES   +9 more
europepmc   +1 more source

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała   +3 more
wiley   +1 more source

Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 346-363, February 2026.
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander   +4 more
wiley   +1 more source

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