Results 211 to 220 of about 158,457 (326)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Computational Medicine: What Electrophysiologists Should Know to Stay Ahead of the Curve. [PDF]

Curr Cardiol Rep
Magoon MJ, Nazer B, Akoum N, Boyle PM.
europepmc   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Long-Term Follow-Up of Inducible Bundle Branch Reentrant Ventricular Tachycardia in Patients Without Structural Heart Disease: Beyond the Electrophysiology Laboratory. [PDF]

J Cardiovasc Electrophysiol
Chokr MO, Filho HHR, Coello RA, Kulchetscki RM, Moura L, Darrieux F, Hachul DT, Sacilotto L, Wu TC, Vandoni PM, Souza IB, Linhares P, Pisani CF, Hardy CA, Scanavacca MI.   +14 more
europepmc   +1 more source

Uncommon and Accessory Electrocardiographic Findings in Brugada Syndrome: A Review. [PDF]

J Clin Med
Micari A, Bellocchi P, Cautela A, Moncada A, Pluchino M, Cusmà-Piccione M, Oreto L, Vizzari G, Dattilo G, Crea P.   +9 more
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Functional Substrate Mapping in Ablation for Scar-Related Ventricular Tachycardia. [PDF]

Rev Cardiovasc Med
Nakahara S, Sato H, Bradfield JS.
europepmc   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

The Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic, Marina Vannucci, Nicolae Moise, Seth H. Weinberg, Jan P. Kucera   +4 more
wiley   +1 more source

Safety of non-anesthesiologist positive pressure ventilation and sedation/analgesia during cardiac electrophysiology (EP) procedures in high-risk patients with known or risk factors for obstructive sleep apnea (OSA). [PDF]

J Interv Card Electrophysiol
Fisher JD, Aldrich T, Lewallen L, Adkins J, Mustehsan MH, Ash Y, Rahmanian M, Knowlton S, Taylor V, O'Shea M, Joseph V.   +10 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source