Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip
The advent of organ‐on‐chip models allows closer emulation of in vivo conditions, leading to effective, less costly, and specific drugs. Although a number of membrane‐based on‐chip models exist, better emulating functional models need to be devised for organ simulations.
Tanmayee Makarand Sathe +1 more
wiley +1 more source
Animal and cellular models of atrial fibrillation: a review. [PDF]
Wu Q +8 more
europepmc +1 more source
Changes in Spinal Neural Circuit Plasticity in a Rat Sciatic Nerve Transection Model
Following sciatic nerve transection (SNT), corticospinal tract (CST) labeling in the lumbar gray matter remained unchanged, whereas motor neurons showed soma atrophy with reduced perisomatic vesicular glutamate transporter 1 (vGlut1) and vesicular acetylcholine transporter (vAchT) inputs.
Katsuyuki Konishi +13 more
wiley +1 more source
Radiofrequency ablation of persistent atrial fibrillation in a patient with dextrocardia and interruption of inferior vena cava in the fluoroless catheterization laboratory: a case report. [PDF]
Du Z +5 more
europepmc +1 more source
Various sodium channel isoforms and their scaffolding proteins are found in four different microdomains in vestibular calyx‐bearing afferents. These microdomains serve different purposes, analogous to the heminode, axon initial segment, and synaptic domains of other types of sensory afferents.
Anna Lysakowski +8 more
wiley +1 more source
Conduction disease in cardiac amyloidosis patients: A case series suggesting a role for left bundle branch area pacing. [PDF]
Mehta OH +3 more
europepmc +1 more source
Using 7‐Tesla fMRI and dynamic causal modelling (DCM), we identified a dual‐route mechanism for high‐precision predictions: direct excitatory modulation from the insula to V1, and indirect inhibitory modulation from the insula to V1 via the pulvinar.
Linzhi Tao +5 more
wiley +1 more source
Arrhythmogenic Implications of Inflammatory Bowel Disease: Its Mechanisms and Treatment Effects. [PDF]
Almasri ES +9 more
europepmc +1 more source
Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała +3 more
wiley +1 more source
Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander +4 more
wiley +1 more source

