, 2006 Andersen-Tawil syndrome (ATS) is a rare condition consisting of ventricular arrhythmias, periodic paralysis, and dysmorphic features. In 2001, mutations in KCNJ2, which encodes the α subunit of the potassium channel Kir2.1, were identified in patients ...
Fish, Frank A +2 more
core +2 more sources
Using Inducible Expression Vector Technology To Create Stable Cell Lines Expressing KCNQ2/3, KCNQ4, And KCNQ3/5 Currents Suitable For Automated Electrophysiology Platforms [PDF]
, 2009 Andrew P. Southan +7 more
openalex +1 more source
Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
Advanced Science, EarlyView.As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
Radiofrequency Catheter Ablation of Atrioventricular Nodal Reentrant Tachycardia: It Is Not Always As It Is Expected [PDF]
, 2004 Observation of Coincident arrhythmias is not uncommon but the co-existence of idiopathic verapamil sensitive left ventricular tachycardia (ILVT) with other arrhythmias is very rare.
Arya, Arash +4 more
core +1 more source
The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep
Advanced Science, EarlyView.Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller +3 more
wiley +1 more source
Techniques for Identification of Left Ventricular Asynchrony for Cardiac Resynchronization Therapy in Heart Failure [PDF]
, 2005 The most recent treatment option of medically refractory heart failure includes cardiac resynchronization therapy (CRT) by biventricular pacing in selected patients in NYHA functional class III or IV heart failure. The widely used marker to indicate left
Peter, Schuster, Svein, Faerestrand
core
Advanced Science, EarlyView.Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang +16 more
wiley +1 more source
Advanced Science, EarlyView.Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
Figure-8 Tachycardia Confined to the Anterior Wall of the Left Atrium [PDF]
, 2004 Incisional atrial tachycardias have been described most frequently in patients with previous corrective surgery for congenital heart defects and mitral valve disease.
Jönsson, Anders +2 more
core +1 more source
Combining Life Cycle Assessment and Circularity Assessment to Analyze Environmental Impacts of the Medical Remanufacturing of Electrophysiology Catheters [PDF]
, 2021 Anna Schulte +2 more
openalex +1 more source