Results 101 to 110 of about 188,005 (360)
Big Data and Artificial Intelligence: Opportunities and Threats in Electrophysiology
The combination of big data and artificial intelligence (AI) is having an increasing impact on the field of electrophysiology. Algorithms are created to improve the automated diagnosis of clinical ECGs or ambulatory rhythm devices.
R. R. van de Leur+11 more
semanticscholar +1 more source
Biological and Mechanical Limitations for Chronic Fast‐Scan Cyclic Voltammetry Sensor Design
Real‐time detection of neurochemicals has demonstrated value in the field of neuroscience. However, current methods have limitations for use in the chronic setting, which is often the ideal environment for research. This article discusses these limitations, as well as technologies that have been developed to overcome them, and provides recommendations ...
Mason L. Perillo+6 more
wiley +1 more source
Functional activity of peptide ion channels in tethered bilayer lipid membranes: Review
Abstract Ion transport across biomembranes plays a major role in living cells. This fundamental function is normally carried out by molecules with both a hydrophobic and a hydrophilic side (amphiphilic molecules), which aggregate within the membrane forming a hydrophilic pore (the ion channel) permitting the selective translocation of permeant ions ...
Rolando Guidelli, Lucia Becucci
wiley +1 more source
Box Isolation of fibrotic areas: A substrate modification approach in atrial fibrillation patients
In the last years, atrial fibrosis was shown to be an independent predictor of procedural failure in patients with paroxysmal and persistent atrial fibrillation.
Fabian Moser+5 more
doaj
We report a transparent, bilayer-nanomesh microelectrode array for concurrent electrophysiology recording and two-photon imaging. Transparent microelectrode arrays have emerged as increasingly important tools for neuroscience by allowing simultaneous ...
Yi Qiang+17 more
semanticscholar +1 more source
Upconversion‐Based Remote Deep Brain Modulation for Therapeutic Dissection of Parkinson's Disease
An upconversion‐based wireless optogenetic strategy enables an all‐optical deep brain modulation solution for treating Parkinson's disease in rodent animals without using electronics or any tethered cables, providing experimental evidence supporting a therapeutic mechanism of STN‐DBS by disruption of anterograde signal transmission along the indirect ...
Wenchong Zhang+13 more
wiley +1 more source
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini+24 more
wiley +1 more source
Shared and Unique Neural Codes for Biological Motion Perception in Humans and Macaque Monkeys
Cross‐species fMRI studies reveal distinct neural mechanisms for biological motion (BM) processing. In humans, the posterior superior temporal sulcus (hpSTS) selectively responds to conspecific BM, while monkeys process BM from both species in the middle temporal area (MT).
Yuhui Cheng+7 more
wiley +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet+9 more
wiley +1 more source
A computational study of the effects of remodelled electrophysiology and mechanics on initiation of ventricular fibrillation in human heart failure [PDF]
The study of pathological cardiac conditions such as arrhythmias, a major cause of mortality in heart failure, is becoming increasingly informed by computational simulation, numerically modelling the governing equations. This can provide insight where experimental work is constrained by technical limitations and/or ethical issues.
arxiv