Results 101 to 110 of about 198,491 (299)

Transcriptome Sequencing Reveals the Molecular Mechanism of Heat Stroke-Induced Myocardial Injury

Journal of Inflammation Research
Jie Xiang,1,2,* Shijie Shao,1,2,* Jie Huang,3 Na Yang,1,2 Fei Guo,4 Baopeng Tang,1,2 Ling Zhang1,2 1Xinjiang Key Laboratory of Cardiac Electrophysiology and Remodeling, Clinical Medical Research Institute, The First Affiliated Hospital of
Xiang J, Shao S, Huang J, Yang N, Guo F, Tang B, Zhang L   +6 more
doaj  

TRPC3‐Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons

Advanced Science, EarlyView.
How localized Ca2+ signals orchestrate neural repair remains unclear. Here, we show that TRPC3‐driven calcium microdomains direct nerve repair by coupling spatially confined Ca2+ signals to axon regeneration. This module operates in injured peripheral neurons and correlates with neuroprotection in Parkinson's disease, revealing a spatial logic for ...
Yu Lu, Jianbo Zhao, Zhenli Xie, Yuan Wang, Ruolin Wang, Bianbian Wang, Chuhan Shen, Yali Chen, Jingyu Yao, Ziyang Li, Huadong Xu, Zuying Chai, Zhuoyu Zhang, Changhe Wang, Rong Huang   +14 more
wiley   +1 more source

Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia

, 2018
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J., Segar, Rachel, Prystowsky, Eric N., Patel, Parin J., Patel, Jyoti Kandlikar   +4 more
core   +1 more source

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

Advanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva, Felipe L. Bacellar, Raquel Amaral, Louis‐Josselin Lavier‐Aydat, Luísa Cortes, Kamal Asadi, Leïla Tirichine, Paulo R. F. Rocha   +7 more
wiley   +1 more source

Bacterial Electrophysiology

Annual Review of Biophysics
Bacterial ion fluxes are involved in the generation of energy, transport, and motility. As such, bacterial electrophysiology is fundamentally important for the bacterial life cycle, but it is often neglected and consequently, by and large, not understood.
Wei-Chang, Lo, Ekaterina, Krasnopeeva, Teuta, Pilizota   +2 more
openaire   +2 more sources

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

The influence of target discriminability on the time course of attentional selection [PDF]

, 2009
A wealth of neurophysiological data has demonstrated that visual attention can selectively enhance target representations early in the visual processing pathway.
Craston, Patrick, Chennu, Sirvas, Chennu, Srivas, Wyble, Brad, Bowman, Howard   +4 more
core  

A Novel Sparse Cellular Labeling System with Tunable Gradients and Long‐Term Stability

Advanced Science, EarlyView.
The Tri‐M (Multi‐recombinase, Multi‐recognition site, and Multi‐nested) sparse cellular labeling system, built upon competitive recombination, integrates transgenic mice with viral injection to achieve tunable and long‐term stable sparse labeling of specific cell types with region selectivity, from sparse populations to individual cells, facilitating ...
Xiaomei Tang, Zhenye Hou, Li Lu, Yige Song, Changdong Chai, Lanfang Li, Yuhang Shen, Shuo Wang, Ya Zhao, Jinyu Zeng, Yiqing Guo, Fuliang Jiang, Zhigao Xiang, Hao Li, Aodi He, Bing Zhang, Youming Lu, Xinyan Li   +17 more
wiley   +1 more source

An active inference strategy for prompting reliable responses from large language models in medical practice

npj Digital Medicine
Continuing advances in Large Language Models (LLMs) are transforming medical knowledge access across education, training, and treatment. Early literature cautions their non-determinism, potential for harmful responses, and lack of quality control.
Roma Shusterman, Allison C. Waters, Shannon O’Neill, Marshall Bangs, Phan Luu, Don M. Tucker   +5 more
doaj   +1 more source

Arrhythmic Risk Stratification in Patients with Arrhythmogenic Cardiomyopathy

Diagnostics
Arrhythmogenic cardiomyopathy is a heart disease in which the heart muscle is replaced by scar tissue. This is the main substrate for the development of malignant ventricular arrhythmias.
Marisa Varrenti, Eleonora Bonvicini, Leandro Fabrizio Milillo, Ilaria Garofani, Marco Carbonaro, Matteo Baroni, Lorenzo Gigli, Giulia Colombo, Federica Giordano, Raffaele Falco, Antonio Frontera, Roberto Menè, Alberto Preda, Sara Vargiu, Patrizio Mazzone, Fabrizio Guarracini   +15 more
doaj   +1 more source