Results 131 to 140 of about 295,841 (379)

An active inference strategy for prompting reliable responses from large language models in medical practice

npj Digital Medicine
Continuing advances in Large Language Models (LLMs) are transforming medical knowledge access across education, training, and treatment. Early literature cautions their non-determinism, potential for harmful responses, and lack of quality control.
Roma Shusterman, Allison C. Waters, Shannon O’Neill, Marshall Bangs, Phan Luu, Don M. Tucker   +5 more
doaj   +1 more source

Transparent arrays of bilayer-nanomesh microelectrodes for simultaneous electrophysiology and two-photon imaging in the brain

Science Advances, 2018
We report a transparent, bilayer-nanomesh microelectrode array for concurrent electrophysiology recording and two-photon imaging. Transparent microelectrode arrays have emerged as increasingly important tools for neuroscience by allowing simultaneous ...
Yi Qiang, P. Artoni, Kyung Jin Seo, Stanislav Culaclii, Victoria Hogan, Xuanyi Zhao, Yiding Zhong, Xun Han, Po-Min Wang, Y. Lo, Yueming Li, Henil A Patel, Yifu Huang, Abhijeet Sambangi, J. S. V. Chu, Wentai Liu, M. Fagiolini, Hui Fang   +17 more
semanticscholar   +1 more source

Ventricular Tachycardia in the Absence of Structural Heart Disease [PDF]

, 2005
In up to 10% of patients who present with ventricular tachycardia (VT), obvious structural heart disease is not identified. In such patients, causes of ventricular arrhythmia include right ventricular outflow tract (RVOT) VT, extrasystoles, idiopathic ...
Appleton, Christopher P, Lester, Steven J, Munger, Thomas M, Scott, Luis R P, Srivathsan, Komandoor   +4 more
core   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source

Endocardial Pacemaker Implantation in Neonates and Infants [PDF]

, 2006
Transvenous pacemaker lead implantation is the preferred method of pacing in adult patients. Lead performance and longevity are superior and the implantation approach can be performed under local anaesthetic with a very low morbidity.
Ayabakan, Canan, Rosenthal, Eric
core   +2 more sources

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

Advanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni, John Guo, Kai Cheng, Luke Daniel Ofria, Oce Bohra, Ram Sagar, Vasiliki Mahairaki, Christian E Badr, Annie Kathuria   +10 more
wiley   +1 more source

Double gene mutations of LRSAM1 and REEP1 and a new REEP1 mutation site found in a patient with amyotrophic lateral sclerosis with subjective paresthesia: A case report

Ibrain, EarlyView., 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. Leucine‐rich repeats and sterility α mutations in motif 1 (LRSAM1) has been proven to be involved in the pathogenesis of ALS.
Ji‐Yao Qin, Zun‐Lin Zhou, Yuan‐Qing Zhou, Ya Chen, Xiao‐Yan Yang, Hai‐Qing Zhang, Zu‐Cai Xu   +6 more
wiley   +1 more source

THE ELECTROPHYSIOLOGY AND PHARMACOLOGY OF LOBSTER NEUROMUSCULAR SYNAPSES [PDF]

, 1959
Harry Grundfest, J. P. Reuben, W. H. Rickles   +2 more
openalex   +1 more source

Pattern of initiation of monomorphic ventricular tachycardia in recorded intracardiac electrograms [PDF]

, 2005
Background: By analyzing stored intracardiac electrograms during spontaneous monomorphic ventricular tachycardia (VT), we examined the patterns of the VT initiation in a group of patients with implantable cardioverter defibrillators (ICDs).
Arya, Arash, Haghjoo, Majid, Sadr-Ameli, Mohammad Ali   +2 more
core   +2 more sources

High‐Throughput MicroED for Probing Ion Channel Dynamics

Advanced Science, EarlyView.
High‐throughput MicroED offers a new approach for visualizing ion channel dynamics. This approach reveals NaK’s sodium binding modes and NaK2CNG’s potassium‐induced selectivity filter dilation and gating. By capturing these distinct structures, this work challenges traditional models of ion channel permeation and selectivity. Abstract Ion channels play
Marc J Gallenito, Max TB Clabbers, Jieye Lin, Johan Hattne, Tamir Gonen   +4 more
wiley   +1 more source