Results 271 to 280 of about 295,841 (379)

Senescent Microglia Mediate Neuroinflammation‐Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1

Aging Cell, EarlyView.
In the CA1, microglia are activated to be responsible for synaptic pruning. However, LPS induces a senescent phenotype in microglia, characterized by the elevated levels of p16, as well as the production of SASPs. These senescent microglia mediate the removal of excitatory synapses selectively, resulting in dendritic spine loss and LTP impairment ...
Kai Liu, Di Fan, Hai‐peng Wu, Xiao‐yi Hu, Qiu‐li He, Xin‐miao Wu, Cui‐na Shi, Jian‐jun Yang, Mu‐huo Ji   +8 more
wiley   +1 more source

Aerobic Exercise Attenuates Autophagy‐Lysosomal Flux Deficits via β2‐AR‐Mediated ESCRT‐III Subunit CHMP4B in Mice With Human MAPT P301L

Aging Cell, EarlyView.
MAPT accumulation inhibited CHMP4B expression and thus disrupted ESCRT‐III‐mediated autophagosome‐lysosome fusion, which induced a vicious cycle between MAPT aggregation and autophagic deficits. Aerobic exercise could effectively block the vicious cycle and reverse autophagic deficits by promoting the β2‐AR‐RXRα‐CHMP4B‐ESCRT‐III pathway, reducing ...
Shu‐Guang Bi, Haitao Yu, Tian‐Long Gao, Jia‐Jun Wu, Yu‐Ming Mao, Juan Gong, Fang‐Zhou Wang, Liu Yang, Jia Chen, Zi‐Chong Lan, Meng‐Ting Shen, Yun‐Juan Nie, Gao‐Shang Chai   +12 more
wiley   +1 more source

Vascular access site management during electrophysiology procedures: a European Heart Rhythm Association survey. [PDF]

Europace
Mills MT, Gupta D, Luther V, Zylla MM, Futyma P, Perrotta L, Mazurek M, Heeger CH, Marcantoni L, Metzner A, Chun JKR.   +10 more
europepmc   +1 more source

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? Episode II: Empathy

Andrology, EarlyView.
Abstract The exploration of gender differences in non‐andrological fields was the core focus of a series of discussions, which took place at the Endocrinology Unit in Modena, Italy in the form of the aporetic dialogue of ancient Greece. This second episode reports the transcript of the actual debate on testosterone's role in defining empathic behavior ...
Giulia Brigante, Clara Lazzaretti, Ali Ahmad, Massimiliano Colzani, Filippo Vignali, Michele Zoli, Manuela Simoni   +6 more
wiley   +1 more source

Electrophysiology and Innervation of the Photosensitive Epistellar Body in the Lesser Octopus Eledone cirrhosa

, 1998
Christopher S. Cobb, R. Williamson
openalex   +2 more sources

Impact of Frailty in Patients With Continuous‐Flow Left Ventricular Assist Device Therapy in End‐Stage Heart Failure: A Systematic Review and Meta‐Analysis

Artificial Organs, EarlyView.
Frailty significantly impacts clinical outcomes in LVAD recipients. This systematic review and meta‐analysis reveal that frail patients experience higher long‐term mortality but comparable short‐term mortality, hospital stay, and complication rates to non‐frail patients.
Christos Costa, Arian Arjomandi Rad, Yi Ting Yu, Nithiananthan Mayooran, Andrew Xanthopoulos, Marinos Koulouroudias, Robert Vardanyan, Gustavo Antonio Guida, Lydia Wilkinson, Jan Schmitto, Arjang Ruhparwar, Alina Zubarevich, Alexander Weymann, Peyman Sardari Nia, Antonios Kourliouros, Thanos Athanasiou   +15 more
wiley   +1 more source

Assessment of User Experience, Acceptability, Usability, Human‐Device Interaction, and Ergonomics in Two Mobile FES‐Cycling Systems for Individuals With Spinal Cord Injury

Artificial Organs, EarlyView.
This study evaluates the user experience, acceptability, usability, ergonomics, and human‐device interaction of two mobile FES‐cycling systems for individuals with spinal cord injury. The findings confirm a positive user experience, along with strong acceptance and usability of both devices, emphasizing their potential to enhance Sport‐Therapy and the ...
Roberta Nossa, Emilia Biffi, Nicole Sanna, Eleonora Diella, Eleonora Guanziroli, Federica Ferrari, Simona Ferrante, Franco Molteni, Alessandra Pedrocchi, Marco Tarabini, Emilia Ambrosini   +10 more
wiley   +1 more source

Mapping of a postinfarction left ventricular aneurysm–dependent macroreentrant ventricular tachycardia

HeartRhythm Case Reports, 2015
Elad Anter, MD, Jianqing Li, MD, Cory M. Tschabrunn, CEPS, Reza Nezafat, PhD, Mark E. Josephson, MD   +4 more
doaj   +1 more source

Cardiogenetics: Closing the knowledge gap in India. [PDF]

Indian Pacing Electrophysiol J
Chockalingam P, Wilde AAM.
europepmc   +1 more source

Quantitative magnetic resonance imaging and the electrophysiology of the carpal tunnel region in floor cleaners.

, 1996
Claude Pierre-Jerome, Svein Ivar Bekkelund, Svein Ivar Mellgren, T. Torbergsen   +3 more
openalex   +2 more sources