Results 51 to 60 of about 590,847 (290)

Analysis of the mechanism of glucose uptake by human body cells in the presence of a biologically active lecithin supplement

Современная наука и инновации, 2023
Analysis of the diet of patients with diabetes mellitus revealed a lack (4-5 g per day) in the consumption of lecithin. Theoretical and practical substantiation of the use of lecithin in food formulations with antidiabetic properties was carried out by ...
V. V. Sadovoy, T. V. Shchedrina, A. S. Khamitsaeva   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

AGOA: A Hydration Procedure and Its Application to the 1-Phenyl-b-Carboline Molecule

Journal of the Brazilian Chemical Society, 2002
A new procedure, named AGOA, has been developed and implemented in a computer program written in FORTRAN 77 to explore the hydration structures of polar solutes using its molecular electrostatic potential (MEP). This procedure can be generalized to polar
Hernandes Marcelo Z., Silva João B. P. da, Longo Ricardo L.   +2 more
doaj  

Electrostatic forces on charged surfaces of bilayer lipid membranes [PDF]

, 2013
Simulating protein-membrane interactions is an important and dynamic area of research. A proper definition of electrostatic forces on membrane surfaces is necessary for developing electromechanical models of protein-membrane interactions. Here we modeled
Mikucki, Michael, Zhou, Y. C.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

INCLUDING GAUGE SYMMETRY IN THE LOCALIZATION MECHANISM OF MASSIVE VECTOR FIELDS // INCLUYENDO SIMETRÍA DE CALIBRE EN EL MECANISMO DE LOCALIZACIÓN DE CAMPOS VECTORIALES MASIVOS

Publicaciones en Ciencias y Tecnología, 2013
On the four-dimensional sector of an AdS5 warped geometry the standard electromagnetic interaction can be simulated by massive vector fields via the Ghoroku - Nakamura localization mechanism.
Rommel Guerrero, Rafael Omar Rodríguez
doaj  

Protonated nucleobases are not fully ionized in their chloride salt crystals and form metastable base pairs further stabilized by the surrounding anions

IUCrJ, 2018
This paper presents experimental charge-density studies of cytosinium chloride, adeninium chloride hemihydrate and guaninium dichloride crystals based on ultra-high-resolution X-ray diffraction data and extensive theoretical calculations.
Prashant Kumar, Malgorzata Katarzyna Cabaj, Aleksandra Pazio, Paulina Maria Dominiak   +3 more
doaj   +1 more source

Applying a potential across a biomembrane: electrostatic contribution to the bending rigidity and membrane instability

, 2007
We investigate the effect on biomembrane mechanical properties due to the presence an external potential for a non-conductive non-compressible membrane surrounded by different electrolytes.
Ambjornsson, Tobias, Hansen, Per Lyngs, Lomholt, Michael A.   +2 more
core   +1 more source

Electrostatic Embedding of Machine Learning Potentials

Journal of Chemical Theory and Computation, 2022
This work presents a variant of an electrostatic embedding scheme that allows the embedding of arbitrary machine learned potentials trained on molecular systems in vacuo. The scheme is based on physically motivated models of electronic density and polarizability, resulting in a generic model without relying on an exhaustive training set.
openaire   +2 more sources

Electrostatic potential in a superconductor [PDF]

Physical Review B, 2002
The electrostatic potential in a superconductor is studied. To this end Bardeen's extension of the Ginzburg-Landau theory to low temperatures is used to derive three Ginzburg-Landau equations - the Maxwell equation for the vector potential, the Schroedinger equation for the wave function and the Poisson equation for the electrostatic potential.
Lipavsky, P., Kolacek, J., Morawetz, K., Brandt, E.   +3 more
openaire   +4 more sources