Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Quantitative Functional Assessment of Patients Undergoing En Bloc Vertebrectomy for Spinal Tumors: A Multi-Segment Motion Analysis Study. [PDF]
Bressan F +10 more
europepmc +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Morning yoga as an embodied regulatory practice: longitudinal changes in children's self-esteem and gratitude following participation in a school-based yoga program. [PDF]
Shiota S, Ohitokata T, Harada H.
europepmc +1 more source
Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl +6 more
wiley +1 more source
When motivation becomes feeling: disentangling the relationship between motivational beliefs and emotions in elementary and secondary physical education. [PDF]
Braksiek M, Pahmeier I, Simonton KL.
europepmc +1 more source
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green +6 more
wiley +1 more source
An analytical framework for efficient and precision-controlled Monte Carlo simulation of heterogeneous targeted alpha therapy microdosimetry. [PDF]
Zhu J, Cao S, Li X, Qi Y, Chen Z.
europepmc +1 more source
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Current status of sodium provision and reduction management in South Korean school meals: a descriptive study. [PDF]
Kwon S, Lee Y, Kim M.
europepmc +1 more source

