Results 41 to 50 of about 8,219,016 (308)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Montessori Yaklaşımın Çocukların Kavram Edinimi Üzerindeki Etkisinin İncelenmesi [PDF]

, 2014
: The main purpose of this research is to examine the effect of Montessori education approach on 4-6-year-old children’s concept acquisition such as school readiness, direction/position, self/social awareness, texture/material, quantity and time ...
Temel, Zeynep Fulya, TORAN, MEHMET
core   +1 more source

Effect of online education on elementary education in India

Journal for Educators, Teachers and Trainers, 2022
The mishaps happening in online education can cost a lot to the students who are getting educated by it in many ways. Elementary students particularly suffer immensely in terms of health, safety due to the online mode of education. The education system for young kids is viewed as a sacred stage since it helps in imparting basic knowledge to a human ...
Srinidhi, S., Vezhaventhan, D., Shoba Jasmin, K. S., Kirubagaran, K., Gopalan, K. R.   +4 more
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Teacher Participation in Online Collaborative Learning: Does It Improve Their Teaching Competency?

Journal of Learning for Development
The Covid-19 pandemic has caused a rapid transformation of Teacher Professional Education (TPE) in Indonesia from face-to-face to online. Although the programme is run online, learning activities, namely collaborative learning among programme ...
Wawan Krismanto, Ahmad Syawaluddin, Sayidiman, Muhammad Irfan   +3 more
doaj   +1 more source

Addition and Subtraction of Fractions Module Based Project Based Learningfor Students of Elementary School

JTAM (Jurnal Teori dan Aplikasi Matematika), 2022
Independent teaching materials in the form of modules containing an understanding of mathematical concepts need to be further developed on a project-based basis.
Dyah Triwahyuningtyas, Novia Eka Mahmuda, Lidya Ristanti Santoso, Nyamik Rahayu Sesanti   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

ARES (Augmented Reality-Ethnoscience): development of digital learning media to improve critical thinking ability in elementary school students

Primary: Jurnal Pendidikan Guru Sekolah Dasar
The 21st century presents various global challenges that require the development of students’ critical thinking skills; however, the lack of contextual digital media to support ecosystem observation has contributed to low levels of students’ critical ...
Zidni Alfian Barif, Apnorlince Paulus, Raihatul Jannah, Alwiana Hamidah Nugroho, Nabila Ariiqah   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Integrating The Traditional Game Gasing: Comparison and Correlation of Responses, Peace-Loving Character, Social Care, and Student Responsibility

Journal of Innovation in Educational and Cultural Research
The era of globalization and the rapid development of technology have made many children prefer online games over traditional games. This makes it difficult for children to socialize with the surrounding environment and have high individual character ...
Alirmansyah Alirmansyah, Muhammad Dewa Zulkhi, Pebri Azmi Pandya, Aqilla Fadia Haya, Vidia Wulandari   +4 more
doaj   +1 more source