Results 61 to 70 of about 1,233,006 (281)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Teardrop and heart orbits of a swinging Atwood's Machine

, 1993
An exact solution is presented for a swinging Atwood's machine. This teardrop-heart orbit is constructed using Hamilton-Jacobi theory. The example nicely illustrates the utility of the Hamilton-Jacobi method for finding solutions to nonlinear mechanical ...
Tufillaro, Nicholas B.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

On the Lucas polynomials and some of their new identities

Advances in Difference Equations, 2018
The main purpose of this paper is, using the elementary and combination methods, to study the arithmetical properties of the Lucas polynomials and to obtain some new and interesting identities for them.
Zhang Jin
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The prediction of emotional exhaustion based on the dimensions of teachers' excitement and excitement [PDF]

پژوهش در نظام‌های آموزشی, 2020
Objective: The purpose of this study was to predict emotional exhaustion based on the dimensions perfectionism and teachers, emotions. Method: The research method was correlation and the statistical population consisted of all elementary school teachers ...
asad hejazi, saadolla hashemi
doaj  

N=1* model superpotential revisited (IR behaviour of N=4 limit)

, 2007
The one-loop contribution to the superpotential, in particular the Veneziano-Yankielowicz potential in N=1 supersymmetric Yang-Mills model is discussed from an elementary field theory method and the matrix model point of view.
Arkani-Hamed N., Arnone S., Arnone S., Cachazo F., Dijkgraaf R., Dijkgraaf R., Dorey N., Ferrari F., G. DI SEGNI, Hailu G., K. YOSHIDA, Klemm A., M. SICCARDI, Naculich S. G., S. ARNONE   +14 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Solving diffraction problems by method of elementary scatterers

Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2011
The method of modeling scattering characteristics of bodies with complex geometry and structure using elementary scatterers, which together reproduce the geometry and structure of initial object, is proposed. The efficiency of this approach is shown by a
A. G. Kyurkchan, N. I. Smirnova
doaj   +1 more source