Results 31 to 40 of about 12,224 (308)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Texture zero neutrino models and their connection with resonant leptogenesis

Nuclear Physics B, 2018
Within the low scale resonant leptogenesis scenario, the cosmological CP asymmetry may arise by radiative corrections through the charged lepton Yukawa couplings.
Avtandil Achelashvili, Zurab Tavartkiladze   +1 more
doaj   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Spontaneous CP breaking in a QCD-like theory

Journal of High Energy Physics
We examine the phase structure of a QCD-like theory at θ ¯ $$ \overline{\theta} $$ = π obtained from supersymmetric SU(N) QCD perturbed by a small amount of supersymmetry breaking via anomaly mediation (AMSB QCD). The spectrum of this theory matches that
Csaba Csáki, Maximilian Ruhdorfer, Taewook Youn   +2 more
doaj   +1 more source

TMDlib2 and TMDplotter: a platform for 3D hadron structure studies

European Physical Journal C: Particles and Fields, 2021
A common library, TMDlib2, for Transverse-Momentum-Dependent distributions (TMDs) and unintegrated parton distributions (uPDFs) is described, which allows for easy access of commonly used TMDs and uPDFs, providing a three-dimensional (3D) picture of the ...
N. A. Abdulov, A. Bacchetta, S. Baranov, A. Bermudez Martinez, V. Bertone, C. Bissolotti, V. Candelise, L. I. Estevez Banos, M. Bury, P. L. S. Connor, L. Favart, F. Guzman, F. Hautmann, M. Hentschinski, H. Jung, L. Keersmaekers, A. Kotikov, A. Kusina, K. Kutak, A. Lelek, J. Lidrych, A. Lipatov, G. Lykasov, M. Malyshev, M. Mendizabal, S. Prestel, S. Sadeghi Barzani, S. Sapeta, M. Schmitz, A. Signori, G. Sorrentino, S. Taheri Monfared, A. van Hameren, A. M. van Kampen, M. Vanden Bemden, A. Vladimirov, Q. Wang, H. Yang   +37 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Studying gaugino masses in supersymmetric model at future 100 TeV pp collider

Journal of High Energy Physics, 2019
We discuss prospects of studying supersymmetric model at future pp circular collider (FCC) with its centre-of-mass energy of ∼ 100 TeV. We pay particular attention to the model in which Wino is lighter than other supersymmetric particles and all the ...
Shoji Asai, So Chigusa, Toshiaki Kaji, Takeo Moroi, Masahiko Saito, Ryu Sawada, Junichi Tanaka, Koji Terashi, Kenta Uno   +8 more
doaj   +1 more source